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Vitamin D status of newborns in New Zealand.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Camargo, Carlos A. Ingham, Tristram Wickens, Kristin Thadhani, Ravi I. Silvers, Karen M. Epton, Michael J. Town, G. Ian Espinola, Janice A. Crane, Julian
Spatial Coverage	New Zealand
Description	Country affiliation: United States Author Affiliation: Camargo CA ( Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, 326 Cambridge Street, Suite 410, Boston, MA 02114, USA. ccamargo@partners.org)
Abstract	Recognition of the important non-skeletal health effects of vitamin D has focused attention on the vitamin D status of individuals across the lifespan. To examine the vitamin D status of newborns, we measured serum levels of 25-hydroxyvitamin D (25(OH)D) in the cord blood of 929 apparently healthy newborns in a population-based study in New Zealand, a country at 41 °S latitude, with strong anti-skin cancer (sun avoidance) campaigns and without vitamin D food fortification. Randomly selected midwives in two regions recruited children. The median cord blood level of 25(OH)D was 44 nmol/l (interquartile range, 29-78 nmol/l). Overall, 19 % of newborns had 25(OH)D levels < 25 nmol/l and 57 % had levels < 50 nmol/l; only 27 % had levels of 75 nmol/l or higher, which are levels associated with optimal health in older children and adults. A multivariable ordinal logistic regression model showed that the strongest determinants of low vitamin D status were winter month of birth and non-European ethnicity. Other determinants of low cord blood 25(OH)D included longer gestational age, younger maternal age and a parental history of asthma. In summary, low levels of vitamin D are common among apparently healthy New Zealand newborns, and are independently associated with several easily identified factors. Although the optimal timing and dosage of vitamin D supplementation require further study, our findings may assist future efforts to correct low levels of 25(OH)D among New Zealand mothers and their newborn children.
File Format	HTM / HTML
ISSN	00071145
Issue Number	7
Volume Number	104
e-ISSN	14752662
Journal	British Journal of Nutrition
Language	English
Publisher	Cambridge University Press (on behalf of The Nutrition Society)
Publisher Date	2010-10-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Nutritional Discipline Sciences Fetal Blood Chemistry Infant, Newborn Blood Nutritional Status Vitamin D Deficiency Epidemiology Vitamin D Analogs & Derivatives Asthma Gestational Age Humans Logistic Models Maternal Age Midwifery New Zealand Parents Seasons Skin Neoplasms Prevention & Control Ethnology Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Medicine

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