NDLI: Primary upper-limb lymphoedema.

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Primary upper-limb lymphoedema.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Vignes, S. Arrault, M. Yannoutsos, A. Blanchard, M.
Description	Country affiliation: France Author Affiliation: Vignes S ( Department of Lymphology, Centre National de Référence des Maladies Vasculaires Rares (lymphÅdèmes primaires), Hôpital Cognacq-Jay, 75015 Paris, France. stephane.vignes@cognacq-jay.fr)
Abstract	BACKGROUND: Lymphoedema is a general term used to designate pathological, regional accumulation of protein-rich fluid. It can be either primary or secondary, and mainly occurs after cancer treatment. OBJECTIVES: To analyse the clinical and lymphoscintigraphic characteristics of primary upper-limb lymphoedema (ULL). METHODS: All of the patients with ULL were recruited at a single Department of Lymphology between January 2007 and December 2011. RESULTS: In total, 60 patients (33 female, 27 male) were enrolled. For the 54 noncongenital lymphoedemas, the mean age at onset was 38·5 (range 3-82) years. Lymphoedema was unilateral in 51 patients (85%). It always affected the hand, and less often the forearm (55%) or upper arm (23%). Eleven patients (18%) developed cellulitis after onset of lymphoedema, and 21 patients (35%) had associated lower-limb lymphoedema (LLL). Forty-six patients (with 49 lymphoedematous limbs) underwent lymphoscintigraphy: axillary lymph node uptake was diminished in 18 (37%), absent in 24 (49%) and normal in seven limbs (14%). Among the 43 patients with unilateral lymphoedema and lymphoscintigraphy, 28 had epitrochlear node visualization, suggesting a rerouting through the deep lymphatic system, with 15 only on the lymphoedematous limb and 22 on the contralateral nonlymphoedematous limb. The median follow-up period was 103 months, and 57/60 patients (95%) considered their lymphoedema to be stable. CONCLUSIONS: Primary ULL appears later in life than LLL, without predominance in either sex. Infectious complications are rare and patients considered the lymphoedema volume stable throughout life.
File Format	HTM / HTML
ISSN	00070963
Issue Number	2
Volume Number	168
e-ISSN	13652133
Journal	British Journal of Dermatology
Language	English
Publisher	Wiley-Blackwell (on behalf of British Association of Dermatologists)
Publisher Date	2013-02-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Dermatology Lymphedema Adolescent Adult Age Of Onset Aged Aged, 80 And Over Bandages Cellulitis Complications Child Child, Preschool Drainage Methods Female Humans Therapy Lymphoscintigraphy Male Middle Aged Physical Therapy Modalities Upper Extremity Young Adult Journal Article
Content Type	Text
Resource Type	Article
Subject	Dermatology

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