NDLI: Incidence trends of keratinocytic skin cancers and melanoma in Israel 2006-11.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Sella, T. Goren, I. Shalev, V. Shapira, H. Zandbank, J. Rosenblum, J. Kimlin, M. G. Chodick, G.
Spatial Coverage	Israel
Description	Country affiliation: Israel Author Affiliation: Sella T ( Medical Division, Maccabi Healthcare Services, Tel Aviv, Israel)
Abstract	BACKGROUND: The incidence of melanoma and keratinocyte cancers (KCs) is rising worldwide. Squamous cell carcinomas (SCCs) and basal cell carcinoma (BCCs) are the most common of all cancers. OBJECTIVES: To determine trends in the incidence of melanoma, BCC and SCC among 1·7 million members of Maccabi Healthcare Services (MHS) from 2006 to 2011. METHODS: Data on patients newly diagnosed with melanoma, SCC and BCC were collected from the MHS Cancer Registry and based on histology reports from the centralized pathology laboratory. Age-specific and overall age-adjusted European standardized rates were computed. Trends were estimated by calculating average annual percentage change (AAPC). RESULTS: During the 6-year study period, 16,079 patients were diagnosed with at least one BCC, 4767 with SCC and 1264 with invasive melanoma. Age-standardized incidence rates were 188, 58 and 17 per 100,000 person years for BCC, SCC and melanoma, respectively. All lesions were more common among men and primarily affected the elderly. BCC rates were stable throughout the study period [AAPC -0·7%, 95% confidence interval (CI) -4·5 to 3·2], while the incidence of SCC increased significantly (AAPC 15·5%, 95% CI 2·6-30·0). In contrast, melanoma rates continuously decreased (AAPC -3·0%, 95%CI -4·5 to -0·1). CONCLUSIONS: The incidence of KC in Israel is high. The disparities in incidence trends between SCC, BCC and melanoma allude to their different aetiologies. These findings underscore the importance of continuous monitoring, education and prevention programmes in a growing high-risk population.
File Format	HTM / HTML
ISSN	00070963
Issue Number	1
Volume Number	172
e-ISSN	13652133
Journal	British Journal of Dermatology
Language	English
Publisher	Wiley-Blackwell (on behalf of British Association of Dermatologists)
Publisher Date	2015-01-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Dermatology Carcinoma, Basal Cell Epidemiology Carcinoma, Squamous Cell Melanoma Skin Neoplasms Adolescent Adult Age Of Onset Aged Aged, 80 And Over Child Child, Preschool Female Humans Incidence Infant Infant, Newborn Israel Male Middle Aged Time Factors Young Adult Journal Article
Content Type	Text
Resource Type	Article
Subject	Dermatology

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