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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Yadav, Saurabh K. Chandra, Pranjal Goyal, Rajendra N. Shim, Yoon-Bo |
| Description | Country affiliation: India Author Affiliation: Yadav SK ( Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee 247667, India.) |
| Abstract | The applications of nanomaterial modified sensors, molecularly imprinting polymer based, aptamer based, and immunosensors have been described in the determination of steroids using electroanalytical techniques. After a brief description of the steroids and assays in biological fluids, the principles of electrochemical detection with the advantages and the limitations of the various sensors are presented. The nanomaterial modified sensors catalyze the oxidation/reduction of steroids and are suitable for sensing them in environmental samples and biological fluids. The determination of steroids based on their reduction has been found more useful in comparison to oxidation as the common metabolites present in the biological fluids do not undergo reduction in the usual potential window and hence, do not interfere in the determination. The sensors based on immunosensors and aptamers were found more sensitive and selective for steroid determination. Conducting polymer modified bio-sensors and microchip devices are suggested as possible future prospects for the ultra sensitive and simultaneous determination of steroids and their metabolites in various samples. |
| File Format | HTM / HTML |
| ISSN | 00032670 |
| Volume Number | 762 |
| e-ISSN | 18734324 |
| Journal | Analytica Chimica Acta |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2013-01-31 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Analytical Discipline Chemistry Biosensing Techniques Methods Chemistry Techniques, Analytical Instrumentation Electrochemistry Nanotechnology Steroids Analysis Animals Chromatography Humans Chemistry Journal Article Research Support, Non-u.s. Gov't Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Spectroscopy Environmental Chemistry Analytical Chemistry Biochemistry |
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