NDLI: Perspectives on a new prescription omega-3 fatty acid, icosapent ethyl, for hypertriglyceridemia

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Perspectives on a new prescription omega-3 fatty acid, icosapent ethyl, for hypertriglyceridemia

Content Provider	Taylor & Francis Online
Author	Jacobson, Terry A.
Abstract	Icosapent ethyl (IPE) is a prescription omega-3 fatty acid drug that significantly decreases triglycerides (TG) and has other beneficial lipid effects, including lowering non-high-density lipoprotein cholesterol and apolipoprotein B, without raising low-density lipoprotein cholesterol in patients with very high TG levels (MARINE trial) and in statin-treated patients with persistently high TG levels (ANCHOR trial). The safety and efficacy profile of IPE supports its use in patients with TG ≥500 mg/dl and provides support for potential use in patients with high TG on statin therapy. A large ongoing outcomes trial (REDUCE-IT) will assess the efficacy of IPE in preventing cardiovascular events in high-risk, statin-treated patients with hypertriglyceridemia. As such, IPE may offer benefits over other dyslipidemia treatment options.
Starting Page	149
Ending Page	161
Page Count	13
File Format	PDF HTM / HTML
ISSN	17584299 17584302
Journal	Clinical Lipidology
Volume Number	9
Issue Number	2
DOI	10.2217/clp.14.10
Language	English
Publisher	Taylor & Francis
Publisher Date	2017-01-18
Access Restriction	Open
Subject Keyword	Eicosapentaenoic acid Hypertriglyceridemia Icosapent ethyl Omega-3 fatty acid Statin Triglycerides
Content Type	Text
Resource Type	Article
Subject	Endocrinology, Diabetes and Metabolism Cardiology and Cardiovascular Medicine

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