NDLI: Oxidative–Antioxidative System in Peripartum Acute Renal Failure and Preeclampsia‐Eclampsia

Content Provider	Taylor & Francis Online
Author	Paydas, Saime Balal, Mustafa Seyrek, Neslihan Canacankatan, Necmiye Kayrın, Levent Karayaylali, Ibrahim
Abstract	Background: Preeclampsia‐eclampsia and acute renal failure in peripartum women can be the cause of mortality and morbidity. There are many different reports about oxidative–antioxidative systems in preeclampsia‐eclampsia. Until now, products of activated oxidative–antioxidative systems were not evaluated in peripartum women with acute renal failure. In this study, our aim was to evaluate the oxidative–antioxidative systems in peripartum women with acute renal failure and/or preeclampsia‐eclampsia. Methods: The study groups consisted of 17 peripartum women (first week of delivery) with acute renal failure (G I), 11 preeclamptic (G II), 11 healthy pregnancy (≥ 30 weeks of pregnancy) (G III), and 11 healthy women (G IV) aged between 18–38 years. Superoxide dismutase (SOD), glutathione peroxidase (GSHPx) in erythrocytes, and plasma malondialdehyde (MDA) levels were measured in all groups. SOD, GSHPx, and MDA levels were also measured at the onset of acute renal failure (G IA), regression of renal dysfunction (G IB) and recovery of renal functions (G IC). Results: MDA levels were 11.95 ± 4.25, 9.22 ± 3.62, 5.10 ± 3.65, 3.40 ± 1.27, 4.91 ± 2.06, 4.24 ± 1.67 mmol/mL in G IA, G IB, G IC, G II, G III, and G IV, respectively. SOD activity in erythrocyte were 3269.23 ± 1437.83, 2641.35 ± 1411.13, 2056.35 ± 1143.11, 924 ± 160.04, 1057.91 ± 257.03, 861.63 ± 243.28 Ug/Hb in G IA, G IB, G IC, G II, G III, and G IV, respectively. GSHPx activity in erythrocyte was 70.17 ± 23.52, 58.27 ± 23.75, 45.44 ± 17.60, 24.48 ± 6.77, 26.28 ± 7.27, 32.95 ± 8.24 Ug/Hb in G IA, G IB, G IC, G II, G III, and G IV, respectively. MDA levels and activities of SOD, GSHPx in erythrocytes were highest in GIA The values of MDA, SOD, and GSH‐Px in G IA, G IB, and G IC were significantly different from each other and decreased while regaining of renal functions. Preeclampsia‐eclampsia or normal pregnancy did not cause elevation of plasma MDA levels and GSHPx, SOD in erythrocyte. Conclusion: Although SOD and GSHPx in erythrocytes and plasma MDA level were found to be similar in healthy women, pregnant women, and preeclamptic women; SOD, GSHPx, and MDA increased at the beginning and decreased during recovery of renal functions in peripartum women with acute renal failure.
Starting Page	625
Ending Page	632
Page Count	8
File Format	PDF HTM / HTML
ISSN	0886022X 15256049
DOI	10.1081/JDI-200037173
Journal	Renal Failure
Volume Number	26
Issue Number	6
Language	English
Publisher	Taylor & Francis
Publisher Date	2009-07-07
Access Restriction	Open
Subject Keyword	Glutathione peroxidase Malondialdehyde Peripartum acute renal failure Superoxide dismutase
Content Type	Text
Resource Type	Article
Subject	Critical Care and Intensive Care Medicine Nephrology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Manganese superoxide dismutase, glutathione peroxidase and catalase gene polymorphisms and clinical outcomes in acute kidney injury

Oxidative stress and enzyme activity in ambulatory renal patients undergoing continuous peritoneal dialysis

Oxidative Stress in Children with Acute Glomerulonephritis

Manganese superoxide dismutase, glutathione peroxidase and catalase gene polymorphisms and clinical outcomes in acute kidney injury

Acute Renal Failure in Pregnancy in South Africa

Acute Renal Failure During Eclampsia: Incidence Risks Factors and Outcome in Intensive Care Unit

Lipid Peroxidation and Antioxidant Enzymes in CAPD Patients

Glutathione and Glycine in Acute Renal Failure

Effect of Hyperbaric Oxygen on Cyclosporine-Induced Nephrotoxicity and Oxidative Stress in Rats

Oxidative–Antioxidative System in Peripartum Acute Renal Failure and Preeclampsia‐Eclampsia

Similar Documents

Manganese superoxide dismutase, glutathione peroxidase and catalase gene polymorphisms and clinical outcomes in acute kidney injury

Oxidative stress and enzyme activity in ambulatory renal patients undergoing continuous peritoneal dialysis

Oxidative Stress in Children with Acute Glomerulonephritis

Manganese superoxide dismutase, glutathione peroxidase and catalase gene polymorphisms and clinical outcomes in acute kidney injury

Acute Renal Failure in Pregnancy in South Africa

Acute Renal Failure During Eclampsia: Incidence Risks Factors and Outcome in Intensive Care Unit

Lipid Peroxidation and Antioxidant Enzymes in CAPD Patients

Glutathione and Glycine in Acute Renal Failure

Effect of Hyperbaric Oxygen on Cyclosporine-Induced Nephrotoxicity and Oxidative Stress in Rats

Oxidative–Antioxidative System in Peripartum Acute Renal Failure and Preeclampsia‐Eclampsia