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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Almad, Akshata A Maragakis, Nicholas J |
| Abstract | Therapeutic strategies using stem cells for treating neurological diseases are receiving more attention as the scientific community appreciates cell-autonomous contributions to several diseases of the central nervous system. The transplantation of stem cells from various sources is now being employed for both neuronal and glial replacement. This review provides an assessment of glial contributions to some of the central nervous system diseases and the advancements in cellular replacement approaches. The rationale for glial replacement in individual diseases and the potential hurdles for cell-replacement strategies are also emphasized. The significant progress in the field of stem cell biology with the advent of tools such as induced pluripotent stem cells and imaging techniques holds promise for the clinical application of cell therapeutics. |
| Related Links | https://stemcellres.biomedcentral.com/counter/pdf/10.1186/scrt128.pdf |
| Ending Page | 7 |
| Page Count | 7 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 17576512 |
| DOI | 10.1186/scrt128 |
| Journal | Stem Cell Research & Therapy |
| Issue Number | 5 |
| Volume Number | 3 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2012-09-28 |
| Access Restriction | Open |
| Subject Keyword | Stem Cells Cell Biology Regenerative Medicine Tissue Engineering Biomedical Engineering and Bioengineering Amyotrophic Lateral Sclerosis Experimental Autoimmune Encephalomyelitis MPTP Multiple System Atrophy Amyotrophic Lateral Sclerosis Patient Regenerative Medicine/Tissue Engineering |
| Content Type | Text |
| Resource Type | Review |
| Subject | Cell Biology Medicine Biochemistry, Genetics and Molecular Biology Molecular Medicine |
| Journal Impact Factor | 7.1/2023 |
| 5-Year Journal Impact Factor | 7.9/2023 |
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