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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Gholami, Leila Nooshabadi, Vajihe Taghdiri Shahabi, Shiva Jazayeri, Marzieh Tarzemany, Rana Afsartala, Zohreh Khorsandi, Khatereh |
| Abstract | Oral mesenchymal stem cells (MSCs) and their secretomes are considered important factors in the field of medical tissue engineering and cell free biotherapy due to their ease of access, differentiation potential, and successful therapeutic outcomes. Extracellular vesicles (EVs) and the conditioned medium (CM) from MSCs are gaining more attraction as an alternative to cell-based therapies due to the less ethical issues involved, and their easier acquisition, preservation, long term storage, sterilization, and packaging. Bone and periodontal regenerative ability of EVs and CM have been the focus of some recent studies. In this review, we looked through currently available literature regarding MSCs’ EVs or conditioned medium and their general characteristics, function, and regenerative potentials. We will also review the novel applications in regenerating bone and periodontal defects. |
| Related Links | https://cellandbioscience.biomedcentral.com/counter/pdf/10.1186/s13578-020-00527-8.pdf |
| Ending Page | 21 |
| Page Count | 21 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 20453701 |
| DOI | 10.1186/s13578-020-00527-8 |
| Journal | Cell & Bioscience |
| Issue Number | 1 |
| Volume Number | 11 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2021-01-12 |
| Access Restriction | Open |
| Subject Keyword | Cell Biology Microbiology Stem Cells Neurobiology Proteomics Extracellular vesicles Mesenchymal stem cells Bone regeneration Periodontal regeneration |
| Content Type | Text |
| Resource Type | Review |
| Subject | Biochemistry, Genetics and Molecular Biology |
| Journal Impact Factor | 6.1/2023 |
| 5-Year Journal Impact Factor | 7/2023 |
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