NDLI: Predictors and outcome of tetanus in newborns in slum areas of Karachi City: a case control study

Content Provider	Springer Nature : BioMed Central
Author	Sohaila, Arjumand Shafiq, Yasir Azim, Shazia Baloch, Benazir Akhtar, Ali Syed Muhammad Tikmani, Shiyam Sunder Brown, Nick
Abstract	Background Tetanus in newborns, is an under-reported public health problem and a major cause of mortality in developing countries. This study aimed to determine the predictors and outcome of tetanus in newborn infants in the slums of Bin-Qasim town, Karachi, Pakistan. Methods We conducted a case–control study at primary health care centers of slums of Bin-Qasim town, area located adjacent to Bin Qasim seaport in Karachi, from January 2003 to December 2013. Cases were infants aged ≤30 days with tetanus, as defined by the World Health Organization. Controls were newborn infants aged ≤30 days without Tetanus, who were referred for a checkup or minor illnesses. The case to control ratio was 1:2. Results We analyzed 26 cases and 52 controls. The case fatality was 70.8%. We identified four independent predictors of Tetanus in newborns: maternal education (only religious education with no formal education OR 51.95; 95% CI 3.69–731), maternal non-vaccination (OR 24.55; 95% CI 1.01–131.77), lack of a skilled birth attendant (OR 44.00; 95% CI 2.30–840.99), and delivery at home (OR 11.54; 95% CI 1.01–131.77). Conclusions We identified several potentially modifiable socio-demographic risk factors for Tetanus in newborns, including maternal education and immunization status, birth site, and lack of a skilled birth attendant. Prioritization of these risk factors could be useful for planning preventive and cost-effective measures.
Related Links	https://bmcresnotes.biomedcentral.com/counter/pdf/10.1186/s13104-015-1301-y.pdf
Ending Page	4
Page Count	4
Starting Page	1
File Format	HTM / HTML
ISSN	17560500
DOI	10.1186/s13104-015-1301-y
Journal	BMC Research Notes
Issue Number	1
Volume Number	8
Language	English
Publisher	BioMed Central
Publisher Date	2015-08-07
Access Restriction	Open
Subject Keyword	Biomedicine Medicine Public Health Life Sciences Tetanus in newborns Slum Bin Qasim seaport Traditional birth attendant Medicine/Public Health
Content Type	Text
Resource Type	Article
Subject	Biochemistry, Genetics and Molecular Biology Medicine
Journal Impact Factor	1.6/2023

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