NDLI: Current randomized control trials, observational studies and meta analysis in off-pump coronary surgery

Content Provider	Springer Nature : BioMed Central
Author	Parissis, Haralabos Lau, Man Chi Parissis, Mondrian Lampridis, Savvas Graham, Victoria Al-Saudi, Reza Mhandu, Peter
Abstract	The off-pump literature is divided into three eras: the “early phase” with results favouring off-pump surgery supported with randomized control trials (RCTs) mainly from Bristol, UK; an “intermediate phase” dominated by the results of the ROOBY trial and finally a more “contemporary phase” whereby the off/on-pump argument is unsettled. Although the literature has failed to project an overall superiority of off-pump versus on-pump surgery, nevertheless, small randomized control trials and large meta-analysis studies are concluding that the incidence of a stroke is less than 1 % when an aortic off-pump techniques (especially the non-touch technique) are advocated in patients with diseased ascending aorta. Furthermore, off-pump combined with hybrid procedures may lead to a reduction of adverse outcome in the aged high-risk population with concomitant poor left ventricular function and co-morbidities.The current review attempts to bring an insight onto the last ten years knowledge on the on/off-pump debate, with an aim to draw some clear conclusions in order to allow practitioners to reflect on the subject.
Related Links	https://cardiothoracicsurgery.biomedcentral.com/counter/pdf/10.1186/s13019-015-0391-x.pdf
Ending Page	14
Page Count	14
Starting Page	1
File Format	HTM / HTML
ISSN	17498090
DOI	10.1186/s13019-015-0391-x
Journal	Journal of Cardiothoracic Surgery
Issue Number	1
Volume Number	10
Language	English
Publisher	BioMed Central
Publisher Date	2015-12-17
Access Restriction	Open
Subject Keyword	Cardiac Surgery Thoracic Surgery Off-pump coronary surgery Coronary artery bypass surgery beating heart surgery RCTs in off-pump surgery Off-pump versus on-pump
Content Type	Text
Resource Type	Review
Subject	Surgery Cardiology and Cardiovascular Medicine Pulmonary and Respiratory Medicine
Journal Impact Factor	1.5/2023
5-Year Journal Impact Factor	1.6/2023

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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