NDLI: A patient-specific three-dimensional couplant pad for ultrasound image-guided radiation therapy: a feasibility study

Content Provider	Springer Nature : BioMed Central
Author	Kim, Heejung Chang, Ah Ram Cho, Sungwoo Ye, Sung-Joon
Abstract	Background A wide application of ultrasound for radiation therapy has been hindered by a few issues such as skin and target deformations due to probe pressure, optical tracking disabilities caused by irregular surfaces and inter-user variations. The purpose of this study was to overcome these barriers by using a patient-specific three-dimensional (3D) couplant pad (CP). Methods A patient skin mold was designed using a skin contour of simulation CT images and fabricated by a 3D printer. A CP was then casted by pouring gelatin solution into a container accommodating the mold. To validate the use of the CP in positioning accuracy and imaging quality, phantom tests were carried out in our ultrasound-based localization system and then daily ultrasound images of four patients were acquired with and without the CP before treatment. Results In the phantom study, the use of CP increased a contrast-to-noise ratio from 2.4 to 4.0. The positioning accuracies in the US scans with and without the CP were less than 1 mm in all directions. In the patient study, the use of CP decreased the centroid offset of the target volume after target position alignment from 4.4 mm to 2.9 mm. One patient with a small volume of target showed a substantial increase in the inter-fractional target contour agreement (from 0.07 (poor agreement) to 0.31 (fair agreement) in Kappa values) by using the CP. Conclusions Our patient-specific 3D CP based on a 3D mold printing technique not only maintained the tracking accuracy but also reduced the inter-user variation, as well as that could potentially improve detectability of optical markers and target visibility for ultrasound image-guided radiotherapy.
Related Links	https://ro-journal.biomedcentral.com/counter/pdf/10.1186/s13014-018-1098-7.pdf
Ending Page	10
Page Count	10
Starting Page	1
File Format	HTM / HTML
DOI	10.1186/s13014-018-1098-7
Journal	Radiation Oncology
Issue Number	1
Volume Number	13
Language	English
Publisher	BioMed Central
Publisher Date	2018-09-03
Access Restriction	Open
Subject Keyword	Cancer Research Oncology Radiotherapy Imaging Radiology 3D couplant Ultrasound IGRT 3D printing
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Oncology
Journal Impact Factor	3.3/2023
5-Year Journal Impact Factor	3.6/2023

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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