NDLI: Impact of caesarean delivery on children’s autism-like behaviours: the mediation of exclusive breastfeeding

Content Provider	Springer Nature : BioMed Central
Author	Qin, Xiaoyun Li, Peixuan Wu, Ya Wang, Xiaoxu Yan, Shuangqin Xu, Yeqing Zhu, Peng Hao, Jiahu Tao, Fangbiao Huang, Kun
Abstract	Background The rate of autism spectrum disorder (ASD) has been rising worldwide, and therefore it is important to identify potential causes of ASD to facilitate early prevention. This study examined the role of breastfeeding and the association between caesarean delivery (CD) and children’s autism spectrum disorder. Methods The data were from the Ma’anshan birth cohort (MABC) in China, that was set up between May 2013 and September 2014. Women within 14 gestational weeks were recruited. The delivery mode was extracted from medical notes and infant feeding was obtained from questionnaire surveys. Autism-like behaviour was assessed using the Checklist for Autism in Toddlers (CHAT-23) when children were 18 months old, and 3 years of age. At 5 years of age, autism-like behaviour was assessed using the Clancy Autism Behavior Scale behavior. Structural equation models tested the mediation effects of breastfeeding between CD and children’s autism spectrum disorder. Results In all, 1520 (48.89%) women gave birth via CD, and 406 (13.86%) children were identified with autism-like behaviours at 18 months. Compared with women giving birth via vaginal delivery, those giving birth via CD were more likely to experience a higher proportion of delayed initiation of breastfeeding (p < 0.01), and delayed onset of lactogenesis (p < 0.01). CD was associated with a lower proportion of exclusive breastfeeding at 4 months after delivery (p = 0.02). Autism-like behaviour was less likely amongst infants with exclusively breastfeeding at 4 months than amongst those not exclusively breastfeeding at 4 months (p < 0.01). SEM indicated that women who gave birth by CD were more likely to stop exclusive breastfeeding in the first 4 months (standard estimations = − 0.04, p = 0.02), and those children who were not exclusively breastfed at 4 months were more likely to have autism-like behaviours (standard estimations = − 0.05, p < 0.01). The associations persisted at 3 years, but not at 5 years. Conclusions Exclusive breastfeeding at 4 months of age mediated the association between caesarean delivery and children’s autism-like behaviours.
Related Links	https://internationalbreastfeedingjournal.biomedcentral.com/counter/pdf/10.1186/s13006-022-00493-6.pdf
Ending Page	14
Page Count	14
Starting Page	1
File Format	HTM / HTML
ISSN	17464358
DOI	10.1186/s13006-022-00493-6
Journal	International Breastfeeding Journal
Issue Number	1
Volume Number	17
Language	English
Publisher	BioMed Central
Publisher Date	2022-07-15
Access Restriction	Open
Subject Keyword	Maternal and Child Health Caesarean delivery Autism-like behaviours Exclusive breastfeeding Infant Children
Content Type	Text
Resource Type	Article
Subject	Obstetrics and Gynecology Pediatrics, Perinatology and Child Health
Journal Impact Factor	2.9/2023
5-Year Journal Impact Factor	3.6/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Impact of breastfeeding during infancy on functional constipation at 3 years of age: the Japan Environment and Children’s Study

Determinants of breastfeeding initiation among mothers in Kuwait

Determinants of exclusive breastfeeding in rural South India

Determinants of non-exclusive breastfeeding practice during the first 6 months after an elective caesarean birth: a prospective cohort study

Breastfeeding, infant formula supplementation, and Autistic Disorder: the results of a parent survey

Does caesarean section have an impact on exclusive breastfeeding? Evidence from four Southeast Asian countries

Validation of the Arabic Maternal Breastfeeding Evaluation Scale (MBFES-A) among Lebanese women

Factors associated with exclusive breastfeeding of children under six months of age in Cote d’Ivoire

Initiation of breastfeeding and prevalence of exclusive breastfeeding at hospital discharge in urban, suburban and rural areas of Zhejiang China

Impact of caesarean delivery on children’s autism-like behaviours: the mediation of exclusive breastfeeding

Similar Documents

Impact of breastfeeding during infancy on functional constipation at 3 years of age: the Japan Environment and Children’s Study

Determinants of breastfeeding initiation among mothers in Kuwait

Determinants of exclusive breastfeeding in rural South India

Determinants of non-exclusive breastfeeding practice during the first 6 months after an elective caesarean birth: a prospective cohort study

Breastfeeding, infant formula supplementation, and Autistic Disorder: the results of a parent survey

Does caesarean section have an impact on exclusive breastfeeding? Evidence from four Southeast Asian countries

Validation of the Arabic Maternal Breastfeeding Evaluation Scale (MBFES-A) among Lebanese women

Factors associated with exclusive breastfeeding of children under six months of age in Cote d’Ivoire

Initiation of breastfeeding and prevalence of exclusive breastfeeding at hospital discharge in urban, suburban and rural areas of Zhejiang China

Impact of caesarean delivery on children’s autism-like behaviours: the mediation of exclusive breastfeeding