NDLI: Evaluation of SARS-CoV-2 viral RNA in fecal samples

Content Provider	Springer Nature : BioMed Central
Author	Mesoraca, Alvaro Margiotti, Katia Viola, Antonella Cima, Antonella Sparacino, Davide Giorlandino, Claudio
Abstract	The need for timely establishment of a complete diagnostic protocol of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is demanded worldwide. We selected 15 positive novel coronavirus disease 19 (COVID-19) patients with mild or no symptom. Initially, fecal samples were negative in the 67% (10/15) of the cases, while 33% (5/10) of the cases were positive. After serial virus RNA testing, 73% (11/15) of the cases resulted positive to fecal specimens. In particular, 15 days after the first positive respiratory specimens test, 6 fecal specimens became positive for SARS-CoV-2 RNA, while 13 respiratory test returned negative result. In conclusion, qRT-PCR assays of fecal specimens, is an important step to control infection, suggesting that samples remained positive for SARS-CoV-2 RNA longer time then respiratory tract samples. Our results enhance the recent knowledge on this emerging infectious disease and offer suggestions for a more complete diagnostic strategy.
Related Links	https://virologyj.biomedcentral.com/counter/pdf/10.1186/s12985-020-01359-1.pdf
Ending Page	3
Page Count	3
Starting Page	1
File Format	HTM / HTML
DOI	10.1186/s12985-020-01359-1
Journal	Virology Journal
Issue Number	1
Volume Number	17
Language	English
Publisher	BioMed Central
Publisher Date	2020-06-30
Access Restriction	Open
Subject Keyword	Virology Acute respiratory syndrome coronavirus 2 (SARS-CoV-2) SARS-CoV-2 viral RNA Novel coronavirus disease 19 (COVID-19) Fecal specimens Respiratory specimens
Content Type	Text
Resource Type	Article
Subject	Virology Infectious Diseases
Journal Impact Factor	4/2023
5-Year Journal Impact Factor	3.8/2023

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