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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Deng, Guofei Bi, Bo Deng, Huachu Fan, Jingyuan Huang, Zhijian Zhang, Changhua He, Yulong |
| Abstract | Background Anemia represents a well-established risk factor for patients diagnosed with gastric cancer, and is often associated with an unfavorable prognosis. In this context, the timely prediction of distant metastasis risk in patients with anemic gastric cancer assumes paramount importance. Methods Information of gastric cancer patients complicated with preoperative anemia in the First Affiliated Hospital of Sun Yat-sen University was collected. The cohort from the First Affiliated Hospital of Guangxi Medical University was used as an external validation set. A Nomogram was established based on the risk factors screened by univariate and multivariate logistic regression analyses. Results A total of 848 gastric cancer patients with preoperative anemia were enrolled. Pyloric obstruction, carcinoma antigen 125, T stage, N stage, tumor size, and preoperative weight loss were independent predictors of distant metastasis in gastric cancer patients with anemia (pā<ā0.05), based on which a nomogram was constructed. The accuracy, reliability and clinical value of the nomogram were evaluated by concordance index, receiver operating characteristic curve, decision curve analysis, calibration curve and showed good stability and clinical predictive value. Conclusions Preoperative anemic gastric cancer patients, complicated with pyloric obstruction, elevated CA125, advanced T and N stage, larger tumor size, and preoperative weight loss, should be paid more attention to distant metastasis. |
| Related Links | https://wjso.biomedcentral.com/counter/pdf/10.1186/s12957-024-03486-3.pdf |
| Ending Page | 13 |
| Page Count | 13 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 14777819 |
| DOI | 10.1186/s12957-024-03486-3 |
| Journal | World Journal of Surgical Oncology |
| Issue Number | 1 |
| Volume Number | 22 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2024-08-01 |
| Access Restriction | Open |
| Subject Keyword | Surgical Oncology Gastric cancer Distant metastasis Anemia Nomogram Prognosis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Oncology Surgery |
| Journal Impact Factor | 2.5/2023 |
| 5-Year Journal Impact Factor | 2.8/2023 |
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