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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Soler-Palacín, Pere de Gracia, Javier González-Granado, Luis Ignacio Martín, Carlos Rodríguez-Gallego, Carlos Sánchez-Ramón, Silvia Group, Lung ID-Signal |
| Abstract | Background Pulmonary complications are common in primary immunodeficiency diseases (PID) and contribute to morbidity and mortality in these patients. However, their varied presentation and a general lack of awareness of PID in this setting make early diagnosis and treatment difficult. The aim of this study was to define the warning signs of PID in patients with respiratory manifestations, the necessary diagnostic tests, and the therapeutic management of both children and adults. Methods A review of the literature was performed, and 43 PID interdisciplinary specialists were consulted. Results This document identifies the pulmonary and extrapulmonary manifestations that should prompt a suspicion of PID, the immunological and respiratory tests that should be included in the diagnostic process according to the level of care, recommendations regarding the use of immunoglobulin replacement therapy according to the specific immunodeficiency, and the minimum recommended immunological and pulmonary monitoring in these patients. Conclusions This document is the first to combine scientific evidence with the opinion of a broad panel of experts specializing in the treatment of patients with immunodeficiencies. It aims to provide a useful tool for all practitioners who are regularly involved in the management of these patients. |
| Related Links | https://respiratory-research.biomedcentral.com/counter/pdf/10.1186/s12931-018-0923-8.pdf |
| Ending Page | 13 |
| Page Count | 13 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| DOI | 10.1186/s12931-018-0923-8 |
| Journal | Respiratory Research |
| Issue Number | 1 |
| Volume Number | 19 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2018-11-12 |
| Access Restriction | Open |
| Subject Keyword | Pneumology Respiratory System Immunoglobulins/deficiency[mesh] Antibodies/deficiency[mesh] Immunoglobulins/administration and dosage[mesh] Respiratory Tract Infections[mesh] Immunologic Deficiency Syndromes[mesh] Pneumology/Respiratory System |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pulmonary and Respiratory Medicine |
| Journal Impact Factor | 4.7/2023 |
| 5-Year Journal Impact Factor | 5.3/2023 |
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