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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Komatsu, Hiroko Yagasaki, Kaori Yamaguchi, Takuhiro |
| Abstract | Background With the widespread use of orally administered anticancer agents, self-management by cancer patients is inevitable, and adherence to medication is becoming the centre of interest in oncology. Methods/Design This mixed-method study is a two-phased approach with a combined quantitative and qualitative design. In the first phase, we will conduct a prospective randomised controlled study to assess the effects of a nurse-led medication self-management programme for patients receiving oral anticancer treatment. Patients with metastatic breast cancer, who have been newly prescribed an oral chemotherapy or a targeted therapy agent will be enrolled in the study. The participants will be randomly assigned to either the medication self-management support programme group (intervention group) or the conventional care group (control group). This will be an open-label study; therefore, neither the patients nor the nurses will be blinded. Nurses will provide patients in the intervention group with information by using the teach-back method, help patients set a goal based on their preferences, and solve problems through follow-up counselling. The primary outcome measure is adherence to medication, to be measured on the basis of the medication possession ratio (MPR), which is the ratio of the number of days of medication supply to the total days at a specified time interval. We hypothesize that the intervention group will have an MPR of ≥90 % that is significantly higher than that of the control group. Secondary outcome measures include self-efficacy, quality of life, psychological distress, severity and interference of symptoms, patient satisfaction, emergency department visits, and hospital admissions. In the second phase, we will conduct focus-group interviews with intervention nurses, and perform a content analysis to understand their role and challenges these nurses will face in the programme while improving patients’ medication adherence. Discussion The present study will be the first Japanese study to evaluate the effects of medication self-management support provided by nurses to patients with metastatic breast cancer who are receiving oral anticancer treatment. The study is characterised by a unique patient-centred approach aiming to help patients manage their medication based on their needs and preferences, with both quantitative and qualitative evaluations. The findings will contribute to the facilitation of medication management in cancer patients. Trial registration UMIN Clinical Trials Registry (UMIN-CTR), Japan, UMIN000016597 . (27 February 2015). |
| Related Links | https://bmcnurs.biomedcentral.com/counter/pdf/10.1186/s12912-016-0130-1.pdf |
| Ending Page | 9 |
| Page Count | 9 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 14726955 |
| DOI | 10.1186/s12912-016-0130-1 |
| Journal | BMC Nursing |
| Issue Number | 1 |
| Volume Number | 15 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2016-02-08 |
| Access Restriction | Open |
| Subject Keyword | Nursing Nursing Management Nursing Research Metastatic breast cancer Adherence Patient-centred care Shared decision making Concordance Patient preference Self-management |
| Content Type | Text |
| Resource Type | Article |
| Subject | Nursing |
| Journal Impact Factor | 3.1/2023 |
| 5-Year Journal Impact Factor | 3.5/2023 |
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