| Author |
Watanabe, Kei Katsumi, Keiichi Ohashi, Masayuki Shibuya, Yohei Izumi, Tomohiro Hirano, Toru Endo, Naoto Kaito, Takashi Yamashita, Tomoya Fujiwara, Hiroyasu Nagamoto, Yukitaka Matsuoka, Yuji Suzuki, Hidekazu Nishimura, Hirosuke Terai, Hidetomi Tamai, Koji Tagami, Atsushi Yamada, Syuta Adachi, Shinji Yoshii, Toshitaka Ushio, Shuta Harimaya, Katsumi Kawaguchi, Kenichi Yokoyama, Nobuhiko Oishi, Hidekazu Doi, Toshiro Kimura, Atsushi Inoue, Hirokazu Inoue, Gen Miyagi, Masayuki Saito, Wataru Nakano, Atsushi Sakai, Daisuke Nukaga, Tadashi Ikegami, Shota Shimizu, Masayuki Futatsugi, Toshimasa Ohtori, Seiji Furuya, Takeo Orita, Sumihisa Imagama, Shiro Ando, Kei Kobayashi, Kazuyoshi Kiyasu, Katsuhito Murakami, Hideki Yoshioka, Katsuhito Seki, Shoji Hongo, Michio Kakutani, Kenichiro Yurube, Takashi Aoki, Yasuchika Oshima, Masashi Takahata, Masahiko Iwata, Akira Endo, Hirooki Abe, Tetsuya Tsukanishi, Toshinori Nakanishi, Kazuyoshi Watanabe, Kota Hikata, Tomohiro Suzuki, Satoshi Isogai, Norihiro Okada, Eijiro Funao, Haruki Ueda, Seiji Shiono, Yuta Nojiri, Kenya Hosogane, Naobumi Ishii, Ken |
| Abstract |
Background To date, there have been little published data on surgical outcomes for patients with PD with thoracolumbar OVF. We conducted a retrospective multicenter study of registry data to investigate the outcomes of fusion surgery for patients with Parkinson’s disease (PD) with osteoporotic vertebral fracture (OVF) in the thoracolumbar junction. Methods Retrospectively registered data were collected from 27 universities and their affiliated hospitals in Japan. In total, 26 patients with PD (mean age, 76 years; 3 men and 23 women) with thoracolumbar OVF who underwent spinal fusion with a minimum of 2 years of follow-up were included (PD group). Surgical invasion, perioperative complications, radiographic sagittal alignment, mechanical failure (MF) related to instrumentation, and clinical outcomes were evaluated. A control group of 296 non-PD patients (non-PD group) matched for age, sex, distribution of surgical procedures, number of fused segments, and follow-up period were used for comparison. Results The PD group showed higher rates of perioperative complications (p < 0.01) and frequency of delirium than the non-PD group (p < 0.01). There were no significant differences in the degree of kyphosis correction, frequency of MF, visual analog scale of the symptoms, and improvement according to the Japanese Orthopaedic Association scoring system between the two groups. However, the PD group showed a higher proportion of non-ambulators and dependent ambulators with walkers at the final follow-up (p < 0.01). Conclusions A similar surgical strategy can be applicable to patients with PD with OVF in the thoracolumbar junction. However, physicians should pay extra attention to intensive perioperative care to prevent various adverse events and implement a rehabilitation regimen to regain walking ability. |
