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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Wang, Erqian Zhao, Xinyu Yang, Jingyuan Chen, Youxin |
| Abstract | Background To investigate swept-source optical coherence tomography angiography (SS-OCTA) for deep choroid visualization and choroidal vascular density (CVD) measurement. Methods Healthy subjects and central serous chorioretinopathy (CSC) patients were recruited for macular SS-OCTA scans. We evaluated OCTA images at various depths to determine an optimal depth for visualizing choroidal vasculatures. We measured CVD with binarized OCTA images at the optimal depth. In healthy subjects, CVD was studied for its correlation with age, axial length (AL), and subfoveal choroidal thickness (SCT). In CSC eyes, CVD was compared with matched controls. Results Ninety-one healthy eyes and 22 CSC eyes were included. SS-OCTA could display deep choroidal vasculatures as dark signals, with 100 μm beneath BM as the optimal depth. In healthy subjects, the CVD at 100 μm beneath BM (56.5 ± 10.9%) was significantly correlated with SCT (P = 0.004) but not with age (P = 0.49) or AL (P = 0.72). In CSC eyes, the CVD at 100 μm beneath BM (62.3 ± 6.6%) was larger than that in 22 matched controls (54.1 ± 8.0%) (P = 0.001). The difference remained statistically significant after adjusting for SCT (P = 0.02). Conclusions SS-OCTA can be used for visualizing deep choroidal vasculatures. CVD measured by OCTA at 100 μm beneath BM is a useful parameter for quantifying choroidal vascular status. |
| Related Links | https://bmcophthalmol.biomedcentral.com/counter/pdf/10.1186/s12886-020-01591-x.pdf |
| Ending Page | 9 |
| Page Count | 9 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 14712415 |
| DOI | 10.1186/s12886-020-01591-x |
| Journal | BMC Ophthalmology |
| Issue Number | 1 |
| Volume Number | 20 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2020-08-05 |
| Access Restriction | Open |
| Subject Keyword | Ophthalmology Optical coherence tomography angiography Swept-source Choroidal vascular density Subfoveal choroidal thickness Central serous chorioretinopathy |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology |
| Journal Impact Factor | 1.7/2023 |
| 5-Year Journal Impact Factor | 2/2023 |
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