NDLI: Severity of low pre-pregnancy body mass index and perinatal outcomes: the Japan Environment and Children’s Study

Content Provider	Springer Nature : BioMed Central
Author	Nakanishi, Kentaro Saijo, Yasuaki Yoshioka, Eiji Sato, Yukihiro Kato, Yasuhito Nagaya, Ken Takahashi, Satoru Ito, Yoshiya Kobayashi, Sumitaka Miyashita, Chihiro Ikeda-Araki, Atsuko Kishi, Reiko
Abstract	Background The extremes of maternal pre-pregnancy body mass index (BMI) are known to be risk factors associated with obstetric and adverse perinatal outcomes. Among Japanese women aged 20 years or older, the prevalence of underweight (BMI < 18.5 kg/m2) was 11.5% in 2019. Maternal thinness is a health problem caused by the desire to become slim. This study aimed to investigate the association between the severity of maternal low pre-pregnancy BMI and adverse perinatal outcomes, including preterm birth (PTB), low birth weight (LBW), and small-for-gestational age (SGA). Methods We conducted a prospective cohort study using data from the Japan Environment and Children’s Study, which recruited pregnant individuals between 2011 and 2014. Pre-pregnancy BMI was categorized as severe-moderate underweight (BMI < 16.9 kg/m2), mild underweight (BMI, 17.0–18.4 kg/m2), low-normal weight (BMI, 18.5–19.9 kg/m2), high-normal weight (BMI, 20.0–22.9 kg/m2), overweight (BMI, 23.0–24.9 kg/m2), and obese (BMI ≥ 25.0 kg/m2). The high-normal weight group was used as the reference for statistical analyses. Adjusted logistic regression was performed to evaluate the association between pre-pregnancy BMI and PTB, LBW, and SGA. Results Of 92,260 singleton pregnant individuals, the prevalence was 2.7% for severe-moderate underweight, 12.9% for mild underweight, and 24.5% for low-normal weight. The prevalence of adverse outcomes was 4.6% for PTB, 8.1% for LBW, and 7.6% for SGA. The adjusted odds ratios (aORs) for PTB were 1.72 (95% confidence interval [CI], 1.46–2.03) for severe-moderate underweight and 1.26 (95% CI, 1.14–1.39) for mild underweight. The aORs of LBW were 2.55 (95% CI, 2.27–2.86) for severe-moderate underweight, 1.64 (95% CI, 1.53–1.76) for mild underweight, and 1.23 (95% CI, 1.16–1.31) for low-normal weight. The aORs of SGA were 2.53 (95% CI, 2.25–2.84) for severe-moderate underweight, 1.66 (95% CI, 1.55–1.79) for mild underweight, and 1.29 (95% CI, 1.21–1.38) for low-normal weight. Conclusions A dose-response relationship was found between the severity of low pre-pregnancy BMI and PTB, LBW, and SGA. Even low-normal BMI (18.5–19.9 kg/m2) increased the risk of LBW and SGA. This study provides useful information for pre-conception counseling in lean individuals.
Related Links	https://bmcpregnancychildbirth.biomedcentral.com/counter/pdf/10.1186/s12884-022-04418-3.pdf
Ending Page	10
Page Count	10
Starting Page	1
File Format	HTM / HTML
ISSN	14712393
DOI	10.1186/s12884-022-04418-3
Journal	BMC Pregnancy and Childbirth
Issue Number	1
Volume Number	22
Language	English
Publisher	BioMed Central
Publisher Date	2022-02-11
Access Restriction	Open
Subject Keyword	Reproductive Medicine Maternal and Child Health Gynecology Adverse perinatal outcomes Low birth weight Maternal body mass index Preterm birth Small-for-gestational age
Content Type	Text
Resource Type	Article
Subject	Obstetrics and Gynecology
Journal Impact Factor	2.8/2023
5-Year Journal Impact Factor	3.4/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China’s two-child policy

Influence of pre-pregnancy body mass index and gestational weight gain in twin pregnancies on blood glucose, serum lipid and perinatal outcomes

Association among pre-pregnancy body mass index, gestational weight gain and neonatal birth weight: a prospective cohort study in China

The association between self-reported total gestational weight gain by pre-pregnancy body mass index and moderate to late preterm birth

Contribution of prepregnancy body mass index and gestational weight gain to adverse neonatal outcomes: population attributable fractions for Canada

Effect of gestational weight gain on adverse birth outcomes in twin pregnancies: a prospective cohort study in Chinese women

Antenatal depressive symptoms and adverse perinatal outcomes

Correlates and outcomes of preterm birth, low birth weight, and small for gestational age in HIV-exposed uninfected infants

Paternal factors and adverse birth outcomes in Lanzhou, China

Severity of low pre-pregnancy body mass index and perinatal outcomes: the Japan Environment and Children’s Study

Similar Documents

Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China’s two-child policy

Influence of pre-pregnancy body mass index and gestational weight gain in twin pregnancies on blood glucose, serum lipid and perinatal outcomes

Association among pre-pregnancy body mass index, gestational weight gain and neonatal birth weight: a prospective cohort study in China

The association between self-reported total gestational weight gain by pre-pregnancy body mass index and moderate to late preterm birth

Contribution of prepregnancy body mass index and gestational weight gain to adverse neonatal outcomes: population attributable fractions for Canada

Effect of gestational weight gain on adverse birth outcomes in twin pregnancies: a prospective cohort study in Chinese women

Antenatal depressive symptoms and adverse perinatal outcomes

Correlates and outcomes of preterm birth, low birth weight, and small for gestational age in HIV-exposed uninfected infants

Paternal factors and adverse birth outcomes in Lanzhou, China

Severity of low pre-pregnancy body mass index and perinatal outcomes: the Japan Environment and Children’s Study