NDLI: Quality indicators in prolonged hemodialysis with regional citrate anticoagulation with the genius system: retrospective cohort of critical patients with acute kidney injury

Content Provider	Springer Nature : BioMed Central
Author	Vieira, Jorge Alberto Menegasso Reinheimer, Isabel Cristina dos Santos, Amanda Corrêa Halperin, Fernando Kowarick Susin, Luiza Aguirre Staub, Lia Portella Ribeiro, Raquel Jaqueline Eder da Silveira, Julia Braga Fontoura, Lucas Friedrich de Souza, Diego Candido Nunes, Karen Patrícia de Souza, Vandrea Carla da Silva Selistre, Luciano Poli-de-Figueiredo, Carlos Eduardo
Abstract	Background Prolonged hemodialysis (HD) is performed from 6 to 12 h and can last up to 24 h. To prevent system clotting some studies suggest that Regional Citrate Anticoagulation (RCA) use reduces bleeding rates relative to systemic heparin. However, there may be difficulties in the patient’s clinical management and completing the prescribed HD with Genius system using RCA. Objective To analyze safety Quality Indicators (IQs) and follow up on prolonged HD with 4% sodium citrate solution in a Genius® hybrid system. Methods This is a retrospective cohort conducted in an intensive care unit. Results 53 random sessions of prolonged HD with 4% sodium citrate solution of critically ill patients with AKI assessed. Evaluated safety indicators were dysnatremia and metabolic alkalosis, observed in 15% and 9.4% of the sessions, respectively. Indicators of effectiveness were system clotting which occurred in 17.3%, and the minimum completion of the prescribed HD time, which was 75.5%. Conclusion The assessment of the indicators showed that the use of RCA with a 4% sodium citrate solution in prolonged HD with the Genius system in critically ill patients with AKI can be performed in a simple, safe, and effective way.
Related Links	https://bmcnephrol.biomedcentral.com/counter/pdf/10.1186/s12882-023-03342-8.pdf
Ending Page	9
Page Count	9
Starting Page	1
File Format	HTM / HTML
ISSN	14712369
DOI	10.1186/s12882-023-03342-8
Journal	BMC Nephrology
Issue Number	1
Volume Number	24
Language	English
Publisher	BioMed Central
Publisher Date	2023-11-30
Access Restriction	Open
Subject Keyword	Nephrology Internal Medicine Regional citrate anticoagulation SLED technique Hybrid renal replacement therapy Sustained low-efficiency dialysis Slow extended dialysis mode
Content Type	Text
Resource Type	Article
Subject	Nephrology
Journal Impact Factor	2.2/2023
5-Year Journal Impact Factor	2.6/2023

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