| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Yang, Chuan-Hua Yu, Miao Wang, Deng-Chao |
| Abstract | Background Pulmonary embolism is a significant clinical challenge with high mortality risk. Computed Tomography Pulmonary Angiography (CTPA) is the gold standard for diagnosis but involves radiation risks. Magnetic Resonance Imaging (MRI) offers a radiation-free alternative, yet its adoption is hindered by inconsistent validation of its diagnostic accuracy. This study systematically assesses MRI’s efficacy in diagnosing pulmonary embolism, incorporating a broad range of literature to ensure comprehensive analysis. Methods Relevant studies on the diagnostic use of MRI for pulmonary embolism were collected through computer searches of PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Database, VIP Database, and China Biology Medicine disc (CBM) databases up to May 12, 2024. Literature was screened based on inclusion and exclusion criteria, data extracted, and study quality assessed according to Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) standards. Data analysis was performed using Stata (versions 17.0 and 14.0) and Meta-Disc 1.4 software. Stata software was used to calculate pooled sensitivity, pooled specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio, and to plot forest plots, hierarchical summary receiver operating characteristic (HSROC) curves, and summary receiver operating characteristic (SROC) curves. The area under the SROC curve (AUC) was calculated, and publication bias was assessed through Deek’s funnel plot, Egger’s test, and Begg’s test. Results Eighteen articles involving 1,264 participants were included. The meta-analysis showed that MRI for the diagnosis of pulmonary embolism had a pooled sensitivity of 0.89 (95% CI: 0.79–0.94) and a specificity of 0.94 (95% CI: 0.89–0.97). The pooled positive likelihood ratio was 14.6 (95% CI: 8.0-26.7) and the negative likelihood ratio was 0.12 (95% CI: 0.06–0.23). The diagnostic odds ratio was 121 (95% CI: 49–299). The AUC of the SROC was 0.97. Deek’s funnel plot suggested potential publication bias in the studies included. Conclusion MRI exhibits high sensitivity and specificity in the diagnosis of pulmonary embolism, demonstrating excellent diagnostic efficacy. Despite potential publication bias, MRI continues to show strong potential for clinical application. |
| Related Links | https://bmcmedimaging.biomedcentral.com/counter/pdf/10.1186/s12880-025-01629-w.pdf |
| Ending Page | 9 |
| Page Count | 9 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| ISSN | 14712342 |
| DOI | 10.1186/s12880-025-01629-w |
| Journal | BMC Medical Imaging |
| Issue Number | 1 |
| Volume Number | 25 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2025-03-20 |
| Access Restriction | Open |
| Subject Keyword | Imaging Radiology Magnetic resonance Pulmonary embolism Meta-analysis |
| Content Type | Text |
| Resource Type | Article |
| Subject | Radiology, Nuclear Medicine and Imaging |
| Journal Impact Factor | 2.9/2023 |
| 5-Year Journal Impact Factor | 2.8/2023 |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|