NDLI: Spatial analysis of HIV-TB co-clustering in Uganda

Content Provider	Springer Nature : BioMed Central
Author	Aturinde, Augustus Farnaghi, Mahdi Pilesjö, Petter Mansourian, Ali
Abstract	Background Tuberculosis (TB) is the leading cause of death for individuals infected with Human immunodeficiency virus (HIV). Conversely, HIV is the most important risk factor in the progression of TB from the latent to the active status. In order to manage this double epidemic situation, an integrated approach that includes HIV management in TB patients was proposed by the World Health Organization and was implemented in Uganda (one of the countries endemic with both diseases). To enable targeted intervention using the integrated approach, areas with high disease prevalence rates for TB and HIV need to be identified first. However, there is no such study in Uganda, addressing the joint spatial patterns of these two diseases. Methods This study uses global Moran’s index, spatial scan statistics and bivariate global and local Moran’s indices to investigate the geographical clustering patterns of both diseases, as individuals and as combined. The data used are TB and HIV case data for 2015, 2016 and 2017 obtained from the District Health Information Software 2 system, housed and maintained by the Ministry of Health, Uganda. Results Results from this analysis show that while TB and HIV diseases are highly correlated (55–76%), they exhibit relatively different spatial clustering patterns across Uganda. The joint TB/HIV prevalence shows consistent hotspot clusters around districts surrounding Lake Victoria as well as northern Uganda. These two clusters could be linked to the presence of high HIV prevalence among the fishing communities of Lake Victoria and the presence of refugees and internally displaced people camps, respectively. The consistent cold spot observed in eastern Uganda and around Kasese could be explained by low HIV prevalence in communities with circumcision tradition. Conclusions This study makes a significant contribution to TB/HIV public health bodies around Uganda by identifying areas with high joint disease burden, in the light of TB/HIV co-infection. It, thus, provides a valuable starting point for an informed and targeted intervention, as a positive step towards a TB and HIV-AIDS free community.
Related Links	https://bmcinfectdis.biomedcentral.com/counter/pdf/10.1186/s12879-019-4246-2.pdf
Ending Page	10
Page Count	10
Starting Page	1
File Format	HTM / HTML
ISSN	14712334
DOI	10.1186/s12879-019-4246-2
Journal	BMC Infectious Diseases
Issue Number	1
Volume Number	19
Language	English
Publisher	BioMed Central
Publisher Date	2019-07-12
Access Restriction	Open
Subject Keyword	Infectious Diseases Parasitology Medical Microbiology Tropical Medicine Internal Medicine HIV TB TB/HIV co-infection Spatial co-clustering Spatial scan statistics Moran’s I Bivariate Moran’s I Uganda
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases
Journal Impact Factor	3.4/2023
5-Year Journal Impact Factor	3.3/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Spatial Co-Clustering of Tuberculosis and HIV in Ethiopia.

The metabolic consequences of HIV/TB co-infection

Bayesian modeling of spatiotemporal patterns of TB-HIV co-infection risk in Kenya

Mortality and associated factors among patients with TB-HIV co-infection in Ethiopia: a systematic review and meta-analysis

Hot-spots of HIV infection in Cameroon: a spatial analysis based on Demographic and Health Surveys data

Predictors of mortality among TB-HIV Co-infected patients being treated for tuberculosis in Northwest Ethiopia: a retrospective cohort study

The spatial-temporal distribution of hepatitis B virus infection in China,2006–2018

Tuberculosis infection control knowledge and attitudes among health workers in Uganda: a cross-sectional study

Outcomes of TB treatment in HIV co-infected TB patients in Ethiopia: a cross-sectional analytic study

Spatial analysis of HIV-TB co-clustering in Uganda

Similar Documents

Spatial Co-Clustering of Tuberculosis and HIV in Ethiopia.

The metabolic consequences of HIV/TB co-infection

Bayesian modeling of spatiotemporal patterns of TB-HIV co-infection risk in Kenya

Mortality and associated factors among patients with TB-HIV co-infection in Ethiopia: a systematic review and meta-analysis

Hot-spots of HIV infection in Cameroon: a spatial analysis based on Demographic and Health Surveys data

Predictors of mortality among TB-HIV Co-infected patients being treated for tuberculosis in Northwest Ethiopia: a retrospective cohort study

The spatial-temporal distribution of hepatitis B virus infection in China,2006–2018

Tuberculosis infection control knowledge and attitudes among health workers in Uganda: a cross-sectional study

Outcomes of TB treatment in HIV co-infected TB patients in Ethiopia: a cross-sectional analytic study

Spatial analysis of HIV-TB co-clustering in Uganda