NDLI: Extracorporeal life support for severe drug-induced cardiotoxicity: a promising therapeutic choice

Content Provider	Springer Nature : BioMed Central
Author	Ashrafian, Hutan Athanasiou, Thanos
Abstract	Drug-induced cardiovascular failure is an acute condition that is associated with significant healthcare consequences. Antidotes and supportive treatments are the initial measures to manage cardiotoxicity, but if severe drug-induced cardiotoxicity develops, usually as cardiovascular shock or cardiac arrest, then circulatory assistance may have an important role in the therapeutic algorithm. A number of circulatory assistance techniques have been increasingly employed to treat severe drug-induced cardiotoxicity. These include extracorporeal membrane oxygenation, intra-aortic balloon pumping and standard cardiopulmonary bypass. Recently, extracorporeal life support (ECLS) has been developed to provide percutaneous cardiopulmonary support peripherally without the need for sternotomy. ECLS can provide successful treatment of severe drug-induced cardiotoxicity in selected cases. This technique may be associated with complications of limb ischaemia, haemorrhage and embolism. An increased consideration of ECLS within the context of rigorous clinical studies and strong evidence can add to its future use for severe drug-induced cardiotoxicity.
Related Links	https://ccforum.biomedcentral.com/counter/pdf/10.1186/cc8046.pdf
Ending Page	2
Page Count	2
Starting Page	1
File Format	HTM / HTML
ISSN	13648535
DOI	10.1186/cc8046
Journal	Critical Care
Issue Number	5
Volume Number	13
Language	English
Publisher	BioMed Central
Publisher Date	2009-09-24
Access Restriction	Open
Subject Keyword	Intensive Critical Care Medicine Emergency Medicine Extracorporeal Membrane Oxygenation Extracorporeal Life Support Refractory Shock Percutaneous Cardiopulmonary Support Overdose Patient
Content Type	Text
Subject	Critical Care and Intensive Care Medicine
Journal Impact Factor	8.8/2023
5-Year Journal Impact Factor	10.4/2023

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