NDLI: Using heart-lung interactions to assess fluid responsiveness during mechanical ventilation

Content Provider	Springer Nature : BioMed Central
Author	Michard, Frédéric Teboul, Jean-Louis
Abstract	According to the Frank-Starling relationship, a patient is a 'responder' to volume expansion only if both ventricles are preload dependent. Mechanical ventilation induces cyclic changes in left ventricular (LV) stroke volume, which are mainly related to the expiratory decrease in LV preload due to the inspiratory decrease in right ventricular (RV) filling and ejection. In the present review, we detail the mechanisms by which mechanical ventilation should result in greater cyclic changes in LV stroke volume when both ventricles are 'preload dependent'. We also address recent clinical data demonstrating that respiratory changes in arterial pulse (or systolic) pressure and in Doppler aortic velocity (as surrogates of respiratory changes in LV stroke volume) can be used to detect biventricular preload dependence, and hence fluid responsiveness in critically ill patients.
Related Links	https://ccforum.biomedcentral.com/counter/pdf/10.1186/cc710.pdf
Ending Page	8
Page Count	8
Starting Page	1
File Format	HTM / HTML
ISSN	13648535
DOI	10.1186/cc710
Journal	Critical Care
Issue Number	5
Volume Number	4
Language	English
Publisher	BioMed Central
Publisher Date	2000-09-01
Access Restriction	Open
Subject Keyword	Intensive Critical Care Medicine Emergency Medicine acute circulatory failure arterial pressure fluid responsiveness left ventricular stroke volume mechanical ventilation pleural pressure preload pulse pressure
Content Type	Text
Resource Type	Review
Subject	Critical Care and Intensive Care Medicine
Journal Impact Factor	8.8/2023
5-Year Journal Impact Factor	10.4/2023

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