NDLI: Intensive care unit-acquired Stenotrophomonas maltophilia: incidence, risk factors, and outcome

Content Provider	Springer Nature : BioMed Central
Author	Nseir, Saad Di Pompeo, Christophe Brisson, Hélène Dewavrin, Florent Tissier, Stéphanie Diarra, Maimouna Boulo, Marie Durocher, Alain
Abstract	Introduction The aim of this study was to determine incidence, risk factors, and impact on outcome of intensive care unit (ICU)-acquired Stenotrophomonas maltophilia. Methods This prospective observational case-control study, which was a part of a cohort study, was conducted in a 30-bed ICU during a three year period. All immunocompetent patients hospitalised >48 hours were eligible. Patients with non-fermenting Gram-negative bacilli (NF-GNB) at ICU admission were excluded. Patients without ICU-acquired S. maltophilia who developed an ICU-acquired NF-GNB other than S. maltophilia were also excluded. Screening (tracheal aspirate and skin, anal, and nasal swabs) for NF-GNB was performed in all patients at ICU admission and weekly. Univariate and multivariate analyses were performed to determine risk factors for ICU-acquired S. maltophilia and for ICU mortality. Results Thirty-eight (2%) patients developed an S. maltophilia ICU-acquired colonisation and/or infection and were all successfully matched with 76 controls. Chronic obstructive pulmonary disease (COPD) and duration of antibiotic treatment (odds ratio [OR] [95% confidence interval (CI)] = 9.4 [3 to 29], p < 0.001, and 1.4 [1 to 2.3], p = 0.001, respectively) were independently associated with ICU-acquired S. maltophilia. Mortality rate (60% versus 40%, OR [95% CI] = 1.3 [1 to 1.7, p = 0.037]), duration of mechanical ventilation (23 ± 16 versus 7 ± 11 days, p < 0.001), and duration of ICU stay (29 ± 21 versus 15 ± 17 days, p < 0.001) were significantly higher in cases than in controls. In addition, ICU-acquired infection related to S. maltophilia was independently associated with ICU mortality (OR [95% CI] = 2.8 [1 to 7.7], p = 0.044). Conclusion COPD and duration of antibiotic treatment are independent risk factors for ICU-acquired S. maltophilia. ICU-acquired S. maltophilia is associated with increased morbidity and mortality rates. ICU-acquired infection related to S. maltophilia is an independent risk factor for ICU mortality.
Related Links	https://ccforum.biomedcentral.com/counter/pdf/10.1186/cc5063.pdf
Ending Page	9
Page Count	9
Starting Page	1
File Format	HTM / HTML
ISSN	13648535
DOI	10.1186/cc5063
Journal	Critical Care
Issue Number	5
Volume Number	10
Language	English
Publisher	BioMed Central
Publisher Date	2006-10-06
Access Restriction	Open
Subject Keyword	Intensive Critical Care Medicine Emergency Medicine Intensive Care Unit Chronic Obstructive Pulmonary Disease Cystic Fibrosis Intensive Care Unit Admission Intensive Care Unit Stay
Content Type	Text
Resource Type	Article
Subject	Critical Care and Intensive Care Medicine
Journal Impact Factor	8.8/2023
5-Year Journal Impact Factor	10.4/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Intensive care unit admission in chronic obstructive pulmonary disease: patient information and the physician’s decision-making process

Intensive care unit-acquired Stenotrophomonas maltophilia: incidence, risk factors, and outcome

Demographics, guidelines, and clinical experience in severe community-acquired pneumonia

Outcomes of Stenotrophomonas maltophilia hospital-acquired pneumonia in intensive care unit: a nationwide retrospective study

Antimicrobial treatment for ventilator-associated tracheobronchitis: a randomized, controlled, multicenter study

Clinical features of invasive bronchial-pulmonary aspergillosis in critically ill patients with chronic obstructive respiratory diseases: a prospective study

Impact of ventilator-associated tracheobronchitis on outcome in patients with chronic obstructive pulmonary disease

Novel insights in ICU-acquired respiratory muscle dysfunction: implications for clinical care

Open access intensive care unit-acquired stenotrophomonas maltophilia: incidence, risk factors, and outcome.

Intensive care unit-acquired Stenotrophomonas maltophilia: incidence, risk factors, and outcome

Similar Documents

Intensive care unit admission in chronic obstructive pulmonary disease: patient information and the physician’s decision-making process

Intensive care unit-acquired Stenotrophomonas maltophilia: incidence, risk factors, and outcome

Demographics, guidelines, and clinical experience in severe community-acquired pneumonia

Outcomes of Stenotrophomonas maltophilia hospital-acquired pneumonia in intensive care unit: a nationwide retrospective study

Antimicrobial treatment for ventilator-associated tracheobronchitis: a randomized, controlled, multicenter study

Clinical features of invasive bronchial-pulmonary aspergillosis in critically ill patients with chronic obstructive respiratory diseases: a prospective study

Impact of ventilator-associated tracheobronchitis on outcome in patients with chronic obstructive pulmonary disease

Novel insights in ICU-acquired respiratory muscle dysfunction: implications for clinical care

Open access intensive care unit-acquired stenotrophomonas maltophilia: incidence, risk factors, and outcome.

Intensive care unit-acquired Stenotrophomonas maltophilia: incidence, risk factors, and outcome