NDLI: Measurement of alveolar derecruitment in patients with acute lung injury: computerized tomography versus pressure

Content Provider	Springer Nature : BioMed Central
Author	Lu, Qin Constantin, Jean-Michel Nieszkowska, Ania Elman, Marilia Vieira, Silvia Rouby, Jean-Jacques
Abstract	Introduction Positive end-expiratory pressure (PEEP)-induced lung derecruitment can be assessed by a pressure–volume (P–V) curve method or by lung computed tomography (CT). However, only the first method can be used at the bedside. The aim of the study was to compare both methods for assessing alveolar derecruitment after the removal of PEEP in patients with acute lung injury or acute respiratory distress syndrome. Methods P–V curves (constant-flow method) and spiral CT scans of the whole lung were performed at PEEPs of 15 and 0 cmH2O in 19 patients with acute lung injury or acute respiratory distress syndrome. Alveolar derecruitment was defined as the difference in lung volume measured at an airway pressure of 15 cmH2O on P–V curves performed at PEEPs of 15 and 0 cmH2O, and as the difference in the CT volume of gas present in poorly aerated and nonaerated lung regions at PEEPs of 15 and 0 cmH2O. Results Alveolar derecruitments measured by the CT and P–V curve methods were 373 ± 250 and 345 ± 208 ml (p = 0.14), respectively. Measurements by both methods were tightly correlated (R = 0.82, p < 0.0001). The derecruited volume measured by the P–V curve method had a bias of -14 ml and limits of agreement of between -158 and +130 ml in comparison with the average derecruited volume of the CT and P–V curve methods. Conclusion Alveolar derecruitment measured by the CT and P–V curve methods are tightly correlated. However, the large limits of agreement indicate that the P–V curve and the CT method are not interchangeable.
Related Links	https://ccforum.biomedcentral.com/counter/pdf/10.1186/cc4956.pdf
Ending Page	10
Page Count	10
Starting Page	1
File Format	HTM / HTML
ISSN	13648535
DOI	10.1186/cc4956
Journal	Critical Care
Issue Number	3
Volume Number	10
Language	English
Publisher	BioMed Central
Publisher Date	2006-06-22
Access Restriction	Open
Subject Keyword	Intensive Critical Care Medicine Emergency Medicine Acute Lung Injury Lung Volume Versus Curve Lung Region Compute Tomography Number
Content Type	Text
Resource Type	Article
Subject	Critical Care and Intensive Care Medicine
Journal Impact Factor	8.8/2023
5-Year Journal Impact Factor	10.4/2023

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Measurement of alveolar derecruitment in patients with acute lung injury: computerized tomography versus pressure–volume curve

Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury

Clinical review: Bedside assessment of alveolar recruitment

Inhaled activated protein C: a novel therapy for acute lung injury?

Influence of positive end-expiratory pressure on cyclic recruitment and derecruitment during one breathing cycle in porcine acute lung injury

Alveolar recruitment can be predicted from airway pressure-lung volume loops: an experimental study in a porcine acute lung injury model

Derecruitment volume assessment derived from pressure–impedance curves with electrical impedance tomography in experimental acute lung injury

Biological markers of lung injury before and after the institution of positive pressure ventilation in patients with acute lung injury

Bench-to-bedside review: Adjuncts to mechanical ventilation in patients with acute lung injury

Measurement of alveolar derecruitment in patients with acute lung injury: computerized tomography versus pressure–volume curve

Similar Documents

Measurement of alveolar derecruitment in patients with acute lung injury: computerized tomography versus pressure–volume curve

Computed tomography assessment of exogenous surfactant-induced lung reaeration in patients with acute lung injury

Clinical review: Bedside assessment of alveolar recruitment

Inhaled activated protein C: a novel therapy for acute lung injury?

Influence of positive end-expiratory pressure on cyclic recruitment and derecruitment during one breathing cycle in porcine acute lung injury

Alveolar recruitment can be predicted from airway pressure-lung volume loops: an experimental study in a porcine acute lung injury model

Derecruitment volume assessment derived from pressure–impedance curves with electrical impedance tomography in experimental acute lung injury

Biological markers of lung injury before and after the institution of positive pressure ventilation in patients with acute lung injury

Bench-to-bedside review: Adjuncts to mechanical ventilation in patients with acute lung injury

Measurement of alveolar derecruitment in patients with acute lung injury: computerized tomography versus pressure–volume curve