NDLI: Glucose–insulin–potassium infusion in sepsis and septic shock: no hard evidence yet

Content Provider	Springer Nature : BioMed Central
Author	van der Horst, Iwan CC Ligtenberg, Jack JM Bilo, Henk JG Zijlstra, Felix Gans, Rijk OB
Abstract	There is no hard evidence yet for a positive effect of glucose–insulin–potassium infusion in sepsis, septic shock or burn patients. Each individual element of the glucose–insulin–potassium regimen, and eventually euglycaemia, should theoretically be beneficial. At present, evidence exists only for reduced mortality with strict metabolic treatment (i.e. blood glucose levels of 4.4–6.1 mmol/l) in critically ill patients admitted to surgical intensive care units, and for better metabolic regulation (i.e. blood glucose levels of 7.0–10.0 mmol/l) in patients with hyperglycaemia and/or diabetes mellitus, and in patients without signs of heart failure (i.e. Killip class I) during acute myocardial infarction.
Related Links	https://ccforum.biomedcentral.com/counter/pdf/10.1186/cc1832.pdf
Ending Page	3
Page Count	3
Starting Page	1
File Format	HTM / HTML
ISSN	13648535
DOI	10.1186/cc1832
Journal	Critical Care
Issue Number	1
Volume Number	7
Language	English
Publisher	BioMed Central
Publisher Date	2002-10-09
Access Restriction	Open
Subject Keyword	Intensive Critical Care Medicine Emergency Medicine euglycaemia glucose insulin myocardial infarction sepsis septic shock
Content Type	Text
Subject	Critical Care and Intensive Care Medicine
Journal Impact Factor	8.8/2023
5-Year Journal Impact Factor	10.4/2023

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Glucose–insulin–potassium infusion in sepsis and septic shock: no hard evidence yet