NDLI: Unusual orbital lymphoma undetectable by magnetic resonance imaging: a case report

Content Provider	Springer Nature : BioMed Central
Author	Tatsugawa, Maria Noma, Hidetaka Mimura, Tatsuya Funatsu, Hideharu
Abstract	Introduction We report the case of a patient with orbital malignant lymphoma that was not detected by imaging studies when she presented with impaired vision, which lead to her eventual loss of sight. Case presentation A 71-year-old Japanese woman complained of deteriorating vision in her left eye. On examination, papilledema was detected, but magnetic resonance imaging only showed slight thickening and enhancement of the left optic nerve. A diagnosis of idiopathic optic neuritis was made and corticosteroid pulse therapy was administered. During the next four months, the patient received a total of four courses of corticosteroid pulse therapy, but she still suffered from bilateral loss of vision. A second magnetic resonance imaging procedure revealed tumors in both orbits and a biopsy showed diffuse large B-cell malignant lymphoma. Conclusion The possibility of malignant lymphoma should be considered in patients with recurrent optic neuropathy despite administration of corticosteroid pulse therapy, even when there are no abnormalities on cerebrospinal fluid examination or magnetic resonance imaging.
Related Links	https://jmedicalcasereports.biomedcentral.com/counter/pdf/10.1186/1752-1947-3-104.pdf
Ending Page	3
Page Count	3
Starting Page	1
File Format	HTM / HTML
ISSN	17521947
DOI	10.1186/1752-1947-3-104
Journal	Journal of Medical Case Reports
Issue Number	1
Volume Number	3
Language	English
Publisher	BioMed Central
Publisher Date	2009-11-03
Access Restriction	Open
Subject Keyword	Medicine Public Health General Practice Family Medicine Primary Care Medicine Surgical Oncology Internal Medicine Optic Nerve Optic Neuritis Optic Neuropathy Papilledema Orbital Tumor Medicine/Public Health
Content Type	Text
Resource Type	Case study
Subject	Medicine
Journal Impact Factor	0.9/2023

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