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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Nakouné, Emmanuel Tricou, Vianney Manirakiza, Alexandre Komoyo, Francis Selekon, Benjamin Gody, Jean Chrysostome Victoir, Kathleen Buchy, Philippe Kazanji, Mirdad |
| Abstract | Background Acute viral respiratory illnesses in children in sub-Saharan Africa have received relatively little attention, although they are much more frequent causes of morbidity and mortality than in developed countries. Active surveillance is essential to identify the causative agents and to improve clinical management, especially in the context of possible circulation of pandemic viruses. Findings A prospective study was conducted in the Central African Republic (CAR) between January and December 2010 among infants and children aged 0–15 years attending sentinel sites for influenza-like illness or acute respiratory illness. Nasopharyngeal swabs were collected, and one-step real-time and multiplex reverse transcription-polymerase chain reaction were used to detect respiratory viruses. Respiratory viruses were detected in 49 of the 329 (14.9%) nasopharyngeal samples: 29 (8.8%) contained influenza viruses (5 (1.5%) had pandemic influenza A/H1N1 virus and 24 (7.3%) had influenza B viruses), 11 (3.3%) contained parainfluenza viruses types 1 and 3 and 9 (2.7%) contained human respiratory syncytial virus. Most cases were detected during the rainy season in the CAR. Analysis of the amplicon sequences confirmed the identity of each detected virus. Conclusions The influenza surveillance system in the CAR has provided valuable data on the seasonality of influenza and the circulation of other respiratory viruses. Our network could therefore play a valuable role in the prevention and control of influenza epidemics in the CAR. |
| Related Links | https://virologyj.biomedcentral.com/counter/pdf/10.1186/1743-422X-10-49.pdf |
| Ending Page | 6 |
| Page Count | 6 |
| Starting Page | 1 |
| File Format | HTM / HTML |
| DOI | 10.1186/1743-422X-10-49 |
| Journal | Virology Journal |
| Issue Number | 1 |
| Volume Number | 10 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2013-02-08 |
| Access Restriction | Open |
| Subject Keyword | Virology Molecular diagnosis Acute respiratory illness Pandemic influenza A/H1N1 2009 Influenza B Respiratory syncytial virus Parainfluenza virus Pediatric patients |
| Content Type | Text |
| Resource Type | Article |
| Subject | Virology Infectious Diseases |
| Journal Impact Factor | 4/2023 |
| 5-Year Journal Impact Factor | 3.8/2023 |
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