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| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Dzenkeviciute, V. Ryliskyte, L. Petrulioniene, Z. Badariene, J. Laucevicius, A. |
| Abstract | There is some evidence that in MetS increase of arterial stiffness may be distributed over muscular and the elastic arteries not uniformly.The purpose of this study was to examine the association between the MS and arterial stiffness of both elastic and muscular arteries in middle aged individuals. Methods: The cohort consisted of 951 individuals without MetS (females 338 and males 613), mean ages 54.15 ± 5.88 and 604 with MetS (females 405 and males 199), mean ages 54.41 ± 5.97 (p = 0.69). For this investigation all those with diabetes were excluded. MetS defined according to the ATP III criteria. Following 10 min supine rest, blood pressure, carotid-femoral and carotid-radial PWV (using Sphygmocor v.7) and cardiovascular index CAVI (VaSera VS-100) were measured. All patients underwent detailed assessment of cardiovascular risk factors. Results: Aortic PWV in the MetS group (9.02 +/- 1.53 m/s) was significantly higher (P < 0.001) than in patients without MetS (8.67 +/- 1.58 m/s). There were no significant between-group differences of carotid-radial PWV (MetS 8.92. +/- 1.21 m/s, without MetS: 8.95 +/- 1.4 m/s; p = 0.53) or CAVI (MetS: 7.93 +/- 3.2 m/s, non-MetS: 8.18 +/- 6 m/s; p = 0.46) values. In this study multiple logistic regression revealed that aortic but not carotidradial PWV and CAVI were independently related to MetS (standardized regression parameter r=−1.25, p= 0.0049 after adjusting for age, gender). Conclusions: the results therefore indicated that elastic arteries may stiffen preferentially over muscular arteries in middle aged individuals with the metabolic syndrome. |
| Related Links | https://arteryresearch.biomedcentral.com/counter/pdf/10.1016/j.artres.2009.10.018.pdf |
| Ending Page | 177 |
| Page Count | 1 |
| Starting Page | 177 |
| File Format | HTM / HTML |
| ISSN | 18764401 |
| DOI | 10.1016/j.artres.2009.10.018 |
| Journal | Artery Research |
| Issue Number | 4 |
| Volume Number | 3 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2009-12-03 |
| Access Restriction | Open |
| Subject Keyword | Medicine Public Health Medicine/Public Health |
| Content Type | Text |
| Resource Type | Synopsis |
| Subject | Physiology (medical) Physiology |
| Journal Impact Factor | 0.9/2023 |
| 5-Year Journal Impact Factor | 0.7/2023 |
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