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Les différentes anomalies de la reproduction masculine sont-elles en augmentation ? Faits et controverses, possibles facteurs en cause: une analyse actualisée des données de la littérature et des registres
| Content Provider | Springer Nature : BioMed Central |
|---|---|
| Author | Auger, J. |
| Abstract | In recent decades, numerous observations in wildlife of various anomalies of the male reproductive functions-some being reminiscent of experimental toxicology data-have raised questions about the possible role of environmental pollutants. A number of studies suggest an increased prevalence of reproductive disorders in adult humans in recent decades in many (but not all) Western countries. The best documented data concern testicular cancer, its increasing rate suggesting that environmental factors and/or changes in lifestyle may come into play. However, considerable regional and ethnic differences exist in absolute incidence rates, suggesting in turn the concomitant role of the genetic background. Finally, several studies suggest that semen quality has declined in many countries. In the early 2000’s, Skakkebæk’s group in Copenhagen postulated a common origin to these different abnormalities — the so-called testicular dysgenesis syndrome (TDS) — all possibly related to abnormal testis development during gestation. Is there a causal link between these different conditions and deleterious environmental and/or lifestyle factors? The answer is far from being unequivocal, and the subject, a potential major public health problem, remains a source of hot debate both within the scientific community and in the media. The present review aims to provide an updated synthesis of these complex issues. |
| Related Links | https://bacandrology.biomedcentral.com/counter/pdf/10.1007/s12610-010-0115-y.pdf |
| Ending Page | 23 |
| Page Count | 17 |
| Starting Page | 7 |
| File Format | HTM / HTML |
| ISSN | 20514190 |
| DOI | 10.1007/s12610-010-0115-y |
| Journal | Basic and Clinical Andrology |
| Issue Number | 1 |
| Volume Number | 21 |
| Language | English |
| Publisher | BioMed Central |
| Publisher Date | 2011-01-14 |
| Access Restriction | Open |
| Subject Keyword | Urology Reproductive Medicine Endocrinology Surgery Gynecology Cancer du testicule Cryptorchidie Environnement Expositions multiples Faibles doses Hypospadias Infertilité masculine Perturbateurs endocriniens Qualité du sperme Style de vie Reprotoxiques Testicule non descendu Cryptorchidism Endocrine disruptors Environment Lifestyle Low doses Male infertility Multiple exposures Semen quality Reproductive toxins Testicular cancer Undescended testicle |
| Content Type | Text |
| Resource Type | Article |
| Subject | Reproductive Medicine Urology |
| Journal Impact Factor | 2.4/2023 |
| 5-Year Journal Impact Factor | 2.6/2023 |
