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| Content Provider | Springer Nature Link |
|---|---|
| Author | Shim, Su Jung Kim, Juree Lim, Sangwook Cho, Sam Ju Lee, Sang Hoon Huh, Hyun Do Chang, Kyung Hwan Shin, Dong Oh |
| Copyright Year | 2014 |
| Abstract | In the research, we evaluated the use of leuco crystal violet (LCV) gel as a dosimeter for therapeutic radiation by investigating its optical characteristics at various component concentrations. We also investigated the aging effect of the LCV gel at different beam energies, doserates, and dosing times to evaluate the LCV’s applicability to radiation therapy. We confirmed that the optimal optical wavelength of the LCV gel dosimeter was 600 nm. The dose sensitivity increased with increasing concentration of LCV; however, the optimal concentration was 1 mM LCV because the transparency of the gel dosimeter is important for use in optical CT scanners. However, the dose sensitivity decreased with increasing concentration of trichloroacetic acid (TAA). Moreover, the transparency of LCV rapidly decreased because of the generation of a white precipitate at TAA concentrations below 25 mM. Thus, an optimal TAA concentration of 30 mM was used in this study. Triton X-100 (8 mM) was identified as the optimal reagent for determining the optimum gel transparency and dose sensitivity. Thus, we present an LCV gel dosimeter composed of 4% gelatin by mass, 1 mM LCV, 30 mM TAA, and 8-mM Triton X-100 for use with an optical CT scanner. We showed good dose linearity up to 30 Gy. There was a little doserate dependency at a beam energy of 6 MV while the doserate dependence was more than 4.2% at a beam energy of 10 MV. To evaluate the energy dependence of the LCV gel dosimeter, we irradiated it at 20 Gy by using 6 MV and 10 MV beams. At the high doserate, the difference in the dose energy dependence was relatively small at approximately 1%, but the difference increased to 4.6% at the low doserate. With respect to the radiation absorbance at a photon energy of 6 MV, the absorbance at an electron energy of 6 MeV decreased by 5.4%, and the absorbances at 9, 12, and 15 MeV increased by 3, 18.7, and 12.2%, respectively. Furthermore, the aging effect was larger in the low-dose group then in the high-dose group. Moreover, we observed that the absorbance between 24 and 48 h after irradiation increased by approximately 5% at 5 Gy. For gel groups tested at high doses, the aging effect was reduced by approximately 1%. |
| Starting Page | 1063 |
| Ending Page | 1069 |
| Page Count | 7 |
| File Format | |
| ISSN | 03744884 |
| Journal | Journal of the Korean Physical Society |
| Volume Number | 64 |
| Issue Number | 7 |
| e-ISSN | 19768524 |
| Language | English |
| Publisher | The Korean Physical Society |
| Publisher Date | 2014-04-23 |
| Publisher Place | Seoul |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Leuco crystal violet gel Radiochromic gel Theoretical, Mathematical and Computational Physics Threedimensional dose evaluation Gel dosimetry Physics Particle and Nuclear Physics Volumetric radiation dosimeter |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physics and Astronomy |
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