NDLI: Cucurbituril-Induced Supramolecular pK $_{a}$ Shift in Fluorescent Dyes and Its Prospective Applications

Please wait, while we are loading the content...

Partial Molar Volume, Partial Molar Adiabatic Compressibility and Viscosity Coefficient of Aqueous Solution of Metal(II) Chelates of Ethylenediaminetetraacetic Acid

Mixed Convection with Thermal Radiation in a Vertical Pipe with Partially Heated or Cooled Wall

Homotopy Perturbation Method (HPM) Solution for Flow of a Conducting Visco-elastic Fluid Through a Porous Medium

Soret and Hall Effect on Heat and Mass Transfer in MHD Free Convective Flow Through a Porous Medium in a Vertical Porous Channel

Two-Dimensional Approximation of Piezoelectric Shallow Shells with Variable Thickness

Nonlinear Oscillator: Controlled and Uncontrolled Vibrations

A Study on the Interacting Ricci Dark Energy in f(R, T) Gravity

Delineation of Natural and Anthropogenic Process Controlling Hydrogeochemistry of Layered Aquifer Sequence

Erratum to: Justification of Koiter’s Shell Model Using Gamma Convergence

Proceedings of the National Academy of Sciences, India Section A: Physical Sciences : Volume 83

Proceedings of the National Academy of Sciences, India Section A: Physical Sciences : Volume 82

Cucurbituril-Induced Supramolecular pK $_{a}$ Shift in Fluorescent Dyes and Its Prospective Applications

Content Provider	Springer Nature Link
Author	Bhasikuttan, Achikanath C. Pal, Haridas Mohanty, Jyotirmayee Barooah, Nilotpal
Copyright Year	2013
Abstract	This review article provides an account on the supramolecular pK $_{a}$ shifts of cucurbit[7]uril-based assemblies of three chromophoric dyes, coumarin 6, Hoechst 33258 and neutral red. Since cucurbituril macrocycles act as cation-receptors due to the presence of two identical negatively polarized carbonyl portals, they preferentially encapsulate the protonated dye/drug over their unprotonated forms, resulting in pronounced pK $_{a}$ shifts of the guest molecules, as large as ~5.2 units. Since the stability and activity of dyes/drugs are often linked to their protonation state, the supramolecular encapsulation by CB7 and the resulting pK $_{a}$ shifts can be rationally exploited to activate drug molecules through thermal/metal ion-responsive pK $_{a}$ tuning, or photo-triggered pH-jump etc. This could act as a simple stimulus for the controlled dissociation of the complex and can make the active protonated/deprotonated form of the guest available for the desired effects. The detailed experimentation on the studied supramolecular host–guest assemblies involving the selected dyes, the associated pK $_{a}$ shifts and the stimuli-responsive pK $_{a}$ tuning, demonstrates their applications in the controlled uptake and release of drugs and photofunctional devices such as logic gates.
Starting Page	1
Ending Page	17
Page Count	17
File Format	PDF
ISSN	03698203
Journal	Proceedings of the National Academy of Sciences, India Section A: Physical Sciences
Volume Number	84
Issue Number	1
e-ISSN	22501762
Language	English
Publisher	Springer India
Publisher Date	2013-11-17
Publisher Place	India
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Applied and Technical Physics Stimuli responsive tuning Protolytic equilibrium Fluorescence Atomic, Molecular, Optical and Plasma Physics pK $_{a}$ shift Quantum Physics Host–guest interaction Physics Cucurbituril
Content Type	Text
Resource Type	Article
Subject	Physics and Astronomy Biochemistry, Genetics and Molecular Biology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Fluorescent Supramolecular Polymers Formed by Crown Ether-Based Host-Guest Interaction

Cucurbituril-based Supramolecular Assemblies of Fluorescent Dyes : Their Prospective Applications

Cucurbituril—assisted sensitive fluorescence detection and quantitation of naproxen drug in wastewater samples: Guest-host characterization and HPLC investigation

Stimuli-responsive polymeric materials functioning via host–guest interactions

Fluorescence Resonance Energy Transfer Systems in Supramolecular Macrocyclic Chemistry

Host–guest interactions of hemicucurbiturils with aminophenols

Integrating Stimuli-Responsive Properties in Host-Guest Supramolecular Drug Delivery Systems

Fluorescent Thienothiophene-Containing Squaraine Dyes and Threaded Supramolecular Complexes with Tunable Wavelengths between 600–800 nm

Study of interaction between fluorescent dyes and Cucurbituril host in aqueous solution

Cucurbituril-Induced Supramolecular pK $_{a}$ Shift in Fluorescent Dyes and Its Prospective Applications

Similar Documents

Fluorescent Supramolecular Polymers Formed by Crown Ether-Based Host-Guest Interaction

Cucurbituril-based Supramolecular Assemblies of Fluorescent Dyes : Their Prospective Applications

Cucurbituril—assisted sensitive fluorescence detection and quantitation of naproxen drug in wastewater samples: Guest-host characterization and HPLC investigation

Stimuli-responsive polymeric materials functioning via host–guest interactions

Fluorescence Resonance Energy Transfer Systems in Supramolecular Macrocyclic Chemistry

Host–guest interactions of hemicucurbiturils with aminophenols

Integrating Stimuli-Responsive Properties in Host-Guest Supramolecular Drug Delivery Systems

Fluorescent Thienothiophene-Containing Squaraine Dyes and Threaded Supramolecular Complexes with Tunable Wavelengths between 600–800 nm

Study of interaction between fluorescent dyes and Cucurbituril host in aqueous solution

Cucurbituril-Induced Supramolecular pK $_{a}$ Shift in Fluorescent Dyes and Its Prospective Applications