NDLI: Synthesis and anti-osteoporosis potential of two new indirubin-3′-oxime derivatives

Content Provider	Springer Nature Link
Author	Long, Pham Quoc Cuong, Nguyen Manh Hoan, Dang Hoang Choi, Eun Mi Tai, Bui Huu Kim, Young Ho
Copyright Year	2003
Abstract	Two new indirubin-3′-oxime derivatives, indirubin-3′-[O-(3-bromoprop-1-yl)-oxime] (2) and indirubin-3′-[O-(methoxycarbonylmethyl)-oxime] (3) were synthesized. Their structures were confirmed by ESI-MS and NMR spectroscopic method. Both of them (5 μg/mL) significantly caused a elevation of cell growth, alkaline phosphate activity, and mineralization in osteoblastic MC3T3-E1 cells (p<0.05).
Starting Page	22
Ending Page	26
Page Count	5
File Format	PDF
ISSN	17382203
Journal	Journal of the Korean Society for Applied Biological Chemistry
Volume Number	53
Issue Number	1
e-ISSN	2234344X
Language	English
Publisher	Springer-Verlag
Publisher Date	2012-07-26
Publisher Place	New York
Access Restriction	Subscribed
Subject Keyword	anti-osteoporosis semi-synthesis Applied Microbiology Biological Techniques indirubin-3′-oxime Bioorganic Chemistry
Content Type	Text
Resource Type	Article
Subject	Organic Chemistry Biochemistry, Genetics and Molecular Biology

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Synthesis and anti-osteoporosis potential of two new indirubin-3′-oxime derivatives