NDLI: Bladder dysfunction in multiple sclerosis: a 6-year follow-up study

Content Provider	Springer Nature Link
Author	Drulovic, Jelena Mesaros, Sarlota Kisic Tepavcevic, Darija Dujmovic Basuroski, Irena Pekmezovic, Tatjana
Copyright Year	2017
Abstract	Bladder dysfunction (BD) is the most common autonomic disturbance in multiple sclerosis, but often overlooked and undertreated. The purpose of this longitudinal study was to explore the changes in the frequency of BD symptoms in MS cohort after a period of 3 and 6 years of follow-up, as well as to investigate the correlations between the presence of BD symptoms and both clinical characteristics and the health-related quality of life (HRQoL) at each subsequent point of estimation. The study population comprises a cohort of 93 patients with MS (McDonald’s criteria, 2001). At each time point (baseline, and at the 3- and 6-year follow-up) of estimation, Expanded Disability Status Scale, Hamilton Rating Scale for Depression, Fatigue Severity Scale, Szasz Sexual Functioning Scale and HRQoL (measured by MSQoL-54) were assessed. The proportion of patients with at least one symptom of BD significantly increased over time, for both men and women (from 48.1% at baseline to 51.9% after 3 years and to 71.4% after 6 years of follow-up for males and from 45.5% at baseline to 50.0% after 3 years and to 66.7% after 6 years of follow-up for females). The most common BD problem was urgency of urination. The presence of BD was statistically significantly associated with higher level of physical disability, sexual dysfunction and HRQoL at each point of follow-up, for both men and women. Our results suggested outstanding frequency of BD in patients with MS, with increasing tendency over time.
Starting Page	83
Ending Page	90
Page Count	8
File Format	PDF
ISSN	03009009
Journal	Acta Neurologica Belgica
Volume Number	117
Issue Number	1
e-ISSN	22402993
Language	English
Publisher	Springer International Publishing
Publisher Date	2017-01-13
Publisher Place	Cham
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Neurology Multiple sclerosis Neurosciences Medicine/Public Health Bladder dysfunction Neuroradiology Quality of life
Content Type	Text
Resource Type	Article
Subject	Neurology (clinical)

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3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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