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| Content Provider | Springer Nature Link |
|---|---|
| Author | Rana, Abdul Qayyum Shah, Reema |
| Copyright Year | 2012 |
| Abstract | Blepharospasm is seen in many cases of Parkinsonism including progressive supranuclear palsy. These patients usually respond well to botulinum toxin, however some patients subsequently fail to respond to even higher doses of botulinum toxin after an initial good response. They should not be considered failure of treatment with botulinum toxin, as a significant number of these patients have underlying apraxia of eyelid opening in addition to blepharospasm, which may be the cause of failure to respond to botulinum toxin. Combination of eyelid crutches or myomectomy with botulinum toxin is more effective in these patients as compared to an individual treatment modality. In this report, we present two patients with progressive supranuclear palsy who failed to respond to botulinum toxin because they had underlying apraxia of lid opening. Partial myomectomy in one patient and eyelid crutches in the other in combination with botulinum toxin lead to a much better response to botulinum toxin. |
| Starting Page | 95 |
| Ending Page | 96 |
| Page Count | 2 |
| File Format | |
| ISSN | 03009009 |
| Journal | Acta Neurologica Belgica |
| Volume Number | 112 |
| Issue Number | 1 |
| e-ISSN | 22402993 |
| Language | English |
| Publisher | Springer Milan |
| Publisher Date | 2012-01-24 |
| Publisher Place | Milan |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Neurology Botulinum toxin and myectomy Neurosciences Medicine/Public Health Blepharospasm and apraxia of eyelid opening Parkinson’s disease Neuroradiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology (clinical) |
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