NDLI: Genotype-Phenotype Maps

Please wait, while we are loading the content...

Genotype-Phenotype Maps

Content Provider	Springer Nature Link
Author	Stadler, Bärbel M. R. Stadler, Peter F.
Copyright Year	2006
Abstract	The current implementation of the Neo-Darwinian model of evolution typically assumes that the set of possible phenotypes is organized into a highly symmetric and regular space. Most conveniently, a Euclidean vector space is used, representing phenotypic properties by real-valued variables. Computational work on the biophysical genotype-phenotype model of RNA folding, however, suggests a rather different picture. If phenotypes are organized according to genetic accessibility, the resulting space lacks a metric and can be formalized only in terms of a relatively unfamiliar structure. Patterns of phenotypic evolution—such as punctuation, irreversibility, and modularity—result naturally from the properties of the genotype-phenotype map, which, given the genetic accessibility structure, define accessibility in the phenotype space. The classical framework, however, addresses these patterns exclusively in terms of natural selection on suitably constructed fitness landscapes. Recent work has extended the explanatory level for phenotypic evolution from fitness considerations alone to include the topological structure of phenotype space as induced by the genotype-phenotype map. Lewontin’s notion of “quasi-independence” of characters can also be formalized in topological terms: it corresponds to the assumption that a region of the phenotype space is represented by a product space of orthogonal factors. In this picture, each character corresponds to a factor of a region of the phenotype space. We consider any region of the phenotype space that has a given factorization as a “type”, i.e., as a set of phenotypes that share the same set of phenotypic characters. Thus, a theory of character identity can be developed that is based on the correspondence of local factors in different regions of the phenotype space.
Starting Page	268
Ending Page	279
Page Count	12
File Format	PDF
ISSN	15555542
Journal	Biological Theory
Volume Number	1
Issue Number	3
e-ISSN	15555550
Language	English
Publisher	Springer Netherlands
Publisher Date	2015-04-14
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Philosophy of Biology phenotypic characters quasi-independence generalized topology Evolutionary Biology Cognitive Psychology
Content Type	Text
Resource Type	Article
Subject	Ecology, Evolution, Behavior and Systematics History and Philosophy of Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The Delimitation of Phylogenetic Characters

The Causality Horizon and the Developmental Bases of Morphological Evolution

EvoDevo Concepts in the Work of Waddington

The Altruism Paradox: A Consequence of Mistaken Genetic Modeling

Generalized Darwinism and Evolutionary Economics: From Ontology to Theory

Individuality as a Theoretical Scheme. I. Formal and Material Concepts of Individuality

Introns First

Baldwin’s Remarkable Effect

Individuality as a Theoretical Scheme. II. About the Weak Individuality of Organisms and Ecosystems

Genotype-Phenotype Maps

Similar Documents

The Delimitation of Phylogenetic Characters

The Causality Horizon and the Developmental Bases of Morphological Evolution

EvoDevo Concepts in the Work of Waddington

The Altruism Paradox: A Consequence of Mistaken Genetic Modeling

Generalized Darwinism and Evolutionary Economics: From Ontology to Theory

Individuality as a Theoretical Scheme. I. Formal and Material Concepts of Individuality

Introns First

Baldwin’s Remarkable Effect

Individuality as a Theoretical Scheme. II. About the Weak Individuality of Organisms and Ecosystems

Genotype-Phenotype Maps