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| Content Provider | Springer Nature Link |
|---|---|
| Author | El Shwiniy, W. H. Sadeek, S. A. |
| Copyright Year | 2017 |
| Abstract | A new series of metal complexes of Ti(IV), V(IV), Y(III), Zr(IV), Ce(IV) and U(VI) with levofloxacin (Levo) were synthesized and characterized by elemental analysis, molar conductivity, magnetic moment measurements, UV–Vis, FT-IR and $^{1}$H NMR, XRD as well as TG-DTG techniques. The data indicated that levofloxacin reacts as a bidentate ligand chelate to the metal ion through the pyridone oxygen and one carboxylato oxygen. The thermal dehydration and decomposition of the complexes were studied kinetically using Coats–Redfern and Horowitz–Metzger methods, and the thermodynamic data reflected the thermal stability for all complexes. The calculated bond length and the bond stretching force constant, F(U=O), values for UO$_{2}$ bond are 1.86 Å and 690.67 N m$^{−1}$. The biological activities of the levofloxacin, meta-salts and their metal complexes were assayed against different bacterial and fungal species as well as their effect on degradation of calf thymus DNA. |
| Starting Page | 1711 |
| Ending Page | 1723 |
| Page Count | 13 |
| File Format | |
| ISSN | 1735207X |
| Journal | Journal of the Iranian Chemical Society |
| Volume Number | 14 |
| Issue Number | 8 |
| e-ISSN | 17352428 |
| Language | English |
| Publisher | Springer Berlin Heidelberg |
| Publisher Date | 2017-04-09 |
| Publisher Place | Berlin, Heidelberg |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Analytical Chemistry TG Physical Chemistry Levo DNA FT-IR Biochemistry XRD Inorganic Chemistry $^{1}$H NMR Organic Chemistry |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry |
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