NDLI: Application of cellular micropatterns to miniaturized cell-based biosensor

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Non-invasive estimation of intracranial pressure in traumatic brain injury (TBI) using fully-anisotropic Morlet wavelet transform and support vector regression

Biomedical Engineering Letters : Volume 3, Issue 2, June 2013

Biomedical Engineering Letters : Volume 3, Issue 1, March 2013

Biomedical Engineering Letters : Volume 2

Biomedical Engineering Letters : Volume 1

Application of cellular micropatterns to miniaturized cell-based biosensor

Content Provider	Springer Nature Link
Author	Lee, Hyun Jong Han, Sang Won Chung, Ui Seok Koh, Won Gun
Copyright Year	2013
Abstract	Because of strong demands for high throughput or high content cell-based assay, significant efforts have focused on the assay miniaturization by fabricating cell microarray using a variety of cell patterning techniques such as spotting, photolithography or soft lithography and by integrating cell microarray into microfluidic devices. Response of cells cultured on microarray can be monitored by using either electrochemical or optical detection methods. Impedancebased detection and potential-based detection have been widely used for electrochemical detection, while optical detection relies mostly on the fluorescence and bioluminescence-based techniques. Resultant cell microarray-based biosensor can be applied for high throughput/content drug screening and detection of pathogens, pollutants and warfare agents. For the successful application of cell-based biosensors to various areas, multi-phenotypic cell microarray should be developed and cells on microarray must be cultured in 3-dimensional environment as they do in real tissue to obtain accurate response of cells against target analytes.
Starting Page	117
Ending Page	130
Page Count	14
File Format	PDF
ISSN	20939868
Journal	Biomedical Engineering Letters
Volume Number	3
Issue Number	3
e-ISSN	2093985X
Language	English
Publisher	Springer Berlin Heidelberg
Publisher Date	2013-10-09
Publisher Place	Berlin, Heidelberg
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Cell-based biosensor Cell patterning Cell microarray Electrochemical and optical detection High throughput drug screening Biomedical Engineering Biophysics and Biological Physics Biomedicine general Medical and Radiation Physics
Content Type	Text
Resource Type	Article
Subject	Biomedical Engineering

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

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