NDLI: Common and specific cognitive deficits in schizophrenia: relationships to function

Content Provider	Springer Nature Link
Author	Sheffield, Julia M. Gold, James M. Strauss, Milton E. Carter, Cameron S. MacDonald, Angus W. Ragland, J. Daniel Silverstein, Steven M. Barch, Deanna M.
Copyright Year	2013
Abstract	The goals of the present study were to assess the interrelationships among tasks from the MATRICS and CNTRACS batteries, to determine the degree to which tasks from each battery capture unique variance in cognitive dysfunction in schizophrenia, and to determine the ability of tasks from each battery to predict functional outcome. Subjects were 104 schizophrenia patients and 132 healthy control subjects recruited as part of the CNTRACS initiative. All subjects completed four CNTRACS tasks and two tasks from the MATRICS battery: Brief Assessment of Cognition in Schizophrenia Symbol Coding and the Hopkins Verbal Learning Test. Functional outcome was also assessed in the schizophrenia subjects. In both the patient and control groups, we found significant intercorrelations between all higher order cognitive tasks (episodic memory, goal maintenance, processing speed, verbal learning) but minimal relationships with the visual task. For almost all tasks, scores were significantly related to measures of functional outcome, with higher associations between CNTRACS tasks and performance-based measures of function and between one of the MATRICS tasks and self-reported functioning, relative to the other functioning measures. After regressing out variance shared by other tasks, we continued to observe group differences in performance among task residuals, particularly for measures of episodic memory from both batteries, although these residuals did not correlate as robustly with functional outcome as raw test scores. These findings suggest that there exists both shared and specific variance across cognitive tasks related to cognitive and functional impairments in schizophrenia and that measures derived from cognitive neuroscience can predict functional capacity and status in schizophrenia.
Starting Page	161
Ending Page	174
Page Count	14
File Format	PDF
ISSN	15307026
Journal	Cognitive, Affective, & Behavioral Neuroscience
Volume Number	14
Issue Number	1
e-ISSN	1531135X
Language	English
Publisher	Springer US
Publisher Date	2013-09-14
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Cognitive control Schizophrenia Cognitive Psychology Neurosciences
Content Type	Text
Resource Type	Article
Subject	Cognitive Neuroscience Behavioral Neuroscience

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Common and specific cognitive deficits in schizophrenia: relationships to function

Reduced susceptibility to confirmation bias in schizophrenia

RT distributional analysis of cognitive-control-related brain activity in first-episode schizophrenia

Common and specific cognitive deficits in schizophrenia: relationships to function.

Intact emotion-induced recognition bias in neuropsychological patients with executive control deficits

Schizophrenia and emotional rubbernecking

Antipsychotic dose modulates behavioral and neural responses to feedback during reinforcement learning in schizophrenia

Drink alcohol and dim the lights: The impact of cognitive deficits on medial frontal cortex function

Cognitive effort avoidance and detection in people with schizophrenia

Common and specific cognitive deficits in schizophrenia: relationships to function

Similar Documents

Common and specific cognitive deficits in schizophrenia: relationships to function

Reduced susceptibility to confirmation bias in schizophrenia

RT distributional analysis of cognitive-control-related brain activity in first-episode schizophrenia

Common and specific cognitive deficits in schizophrenia: relationships to function.

Intact emotion-induced recognition bias in neuropsychological patients with executive control deficits

Schizophrenia and emotional rubbernecking

Antipsychotic dose modulates behavioral and neural responses to feedback during reinforcement learning in schizophrenia

Drink alcohol and dim the lights: The impact of cognitive deficits on medial frontal cortex function

Cognitive effort avoidance and detection in people with schizophrenia

Common and specific cognitive deficits in schizophrenia: relationships to function