NDLI: Target Plate Material Influence on Fullerene-C$_{60}$ Laser Desorption/Ionization Efficiency

Content Provider	Springer Nature Link
Author	Zeegers, Guido P. Günthardt, Barbara F. Zenobi, Renato
Copyright Year	2016
Abstract	Systematic laser desorption/ionization (LDI) experiments of fullerene-C$_{60}$ on a wide range of target plate materials were conducted to gain insight into the initial ion formation in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. The positive and negative ion signal intensities of precursor, fragment, and cluster ions were monitored, varying both the laser fluence (0–3.53 Jcm$^{−2}$) and the ion extraction delay time (0–950 ns). The resulting species-specific ion signal intensities are an indication for the ionization mechanisms that contribute to LDI and the time frames in which they operate, providing insight in the (MA)LDI primary ionization. An increasing electrical resistivity of the target plate material increases the fullerene-C$_{60}$ precursor and fragment anion signal intensity. Inconel 625 and Ti90/Al6/V4, both highly electrically resistive, provide the highest anion signal intensities, exceeding the cation signal intensity by a factor ~1.4 for the latter. We present a mechanism based on transient electrical field strength reduction to explain this trend. Fullerene-C$_{60}$ cluster anion formation is negligible, which could be due to the high extraction potential. Cluster cations, however, are readily formed, although for high laser fluences, the preferred channel is formation of precursor and fragment cations. Ion signal intensity depends greatly on the choice of substrate material, and careful substrate selection could, therefore, allow for more sensitive (MA)LDI measurements. Graphical Abstract ᅟ
Starting Page	699
Ending Page	708
Page Count	10
File Format	PDF
ISSN	10440305
Journal	Journal of The American Society for Mass Spectrometry
Volume Number	27
Issue Number	4
e-ISSN	18791123
Language	English
Publisher	Springer US
Publisher Date	2016-02-19
Publisher Institution	The American Society for Mass Spectrometry
Publisher Place	New York
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	C$_{60}$ Electrical conductivity Electrical resistivity Electrospray deposition Fullerene Ionization mechanism LDI MALDI Thermal conductivity Analytical Chemistry Biotechnology Organic Chemistry Proteomics Bioinformatics
Content Type	Text
Resource Type	Article
Subject	Spectroscopy Structural Biology

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Laser-Induced Thermal Desorption Facilitates Postsource Decay of Peptide Ions

Laser Pulse Width Dependence and Ionization Mechanism of Matrix-Assisted Laser Desorption/Ionization

Thermal Proton Transfer Reactions in Ultraviolet Matrix-Assisted Laser Desorption/Ionization

Formation of Metal-Related Ions in Matrix-Assisted Laser Desorption Ionization

Ion-to-Neutral Ratios and Thermal Proton Transfer in Matrix-Assisted Laser Desorption/Ionization

Scanning microprobe matrix-assisted laser desorption ionization (SMALDI) mass spectrometry: Instrumentation for sub-micrometer resolved LDI and MALDI surface analysis

OmniSpect: An Open MATLAB-Based Tool for Visualization and Analysis of Matrix-Assisted Laser Desorption/Ionization and Desorption Electrospray Ionization Mass Spectrometry Images

Evaluation of Nanoporous Gold with Controlled Surface Structures for Laser Desorption Ionization (LDI) Analysis: Surface Area Versus LDI Signal Intensity

The influence of material and mesh characteristics on transmission mode desorption electrospray ionization

Target Plate Material Influence on Fullerene-C$_{60}$ Laser Desorption/Ionization Efficiency

Similar Documents

Laser-Induced Thermal Desorption Facilitates Postsource Decay of Peptide Ions

Laser Pulse Width Dependence and Ionization Mechanism of Matrix-Assisted Laser Desorption/Ionization

Thermal Proton Transfer Reactions in Ultraviolet Matrix-Assisted Laser Desorption/Ionization

Formation of Metal-Related Ions in Matrix-Assisted Laser Desorption Ionization

Ion-to-Neutral Ratios and Thermal Proton Transfer in Matrix-Assisted Laser Desorption/Ionization

Scanning microprobe matrix-assisted laser desorption ionization (SMALDI) mass spectrometry: Instrumentation for sub-micrometer resolved LDI and MALDI surface analysis

OmniSpect: An Open MATLAB-Based Tool for Visualization and Analysis of Matrix-Assisted Laser Desorption/Ionization and Desorption Electrospray Ionization Mass Spectrometry Images

Evaluation of Nanoporous Gold with Controlled Surface Structures for Laser Desorption Ionization (LDI) Analysis: Surface Area Versus LDI Signal Intensity

The influence of material and mesh characteristics on transmission mode desorption electrospray ionization

Target Plate Material Influence on Fullerene-C$_{60}$ Laser Desorption/Ionization Efficiency