NDLI: Aggressive behavior: Genetic and physiological mechanisms

Please wait, while we are loading the content...

The effects of the glial cell line-derived neurotrophic factor (GDNF) on the levels of mRNA of apoptotic genes Bax and Bcl-xl in the brain of mice genetically predisposed to pathological behavior

Aggressive behavior: Genetic and physiological mechanisms

Analysis of the polymorphism of organelle DNA to elucidate the phylogeography of Norway spruce in the East European Plain

Russian Journal of Genetics: Applied Research : Volume 5, Issue 3, May 2015

Russian Journal of Genetics: Applied Research : Volume 5, Issue 2, March 2015

Russian Journal of Genetics: Applied Research : Volume 5, Issue 1, January 2015

Russian Journal of Genetics: Applied Research : Volume 4

Russian Journal of Genetics: Applied Research : Volume 3

Russian Journal of Genetics: Applied Research : Volume 2

Russian Journal of Genetics: Applied Research : Volume 1

Aggressive behavior: Genetic and physiological mechanisms

Content Provider	Springer Nature Link
Author	Kudryavtseva, N. N. Markel, A. L. Orlov, Yu. L.
Copyright Year	2015
Abstract	The paper presents a review of the literature on the genetic determination of intraspecific aggressive behavior, one of the most complex and universal forms of social behavior in animals on different rungs of the evolutionary ladder. We consider the existing experimental approaches and new opportunities based on recent molecular technologies. The comprehensive approach allows investigating the evolutionary, genetic, and biological roots of aggression and its manifestations under different environmental and social factors, as well as genetic predispositions. The social importance of the problem is noted. The review considers the phenomenology of aggression and mechanisms that stimulate or prevent it. It is supposed that the main social mechanism deterring aggression in a population is the dominance–subordination relationships. Neurobiological determinants of aggression and the role of hereditary factors in controlling aggressive behavior in animals and humans are considered. By the example of neurochemical brain changes in male mice exposed to repeated aggression in daily agonistic intermale interactions, we present the research model “from behavior to the gene.” It is noted in the discussion that the same genes that influence aggressiveness in human were revealed in the experimental studies in animals of different strains, as well as in knockout and transgenic animals. They include genes for transporters supporting serotonin reuptake and enzymes involved in the synthesis and catabolism of serotonin and catecholamines. In conclusion, we consider the prospects of transcriptome studies and problems of the epigenetic regulation of aggressive behavior.
Starting Page	413
Ending Page	429
Page Count	17
File Format	PDF
ISSN	20790597
Journal	Russian Journal of Genetics: Applied Research
Volume Number	5
Issue Number	4
e-ISSN	20790600
Language	English
Publisher	Pleiades Publishing
Publisher Date	2015-08-15
Publisher Place	Moscow
Access Restriction	Subscribed
Subject Keyword	genetics behavior aggression laboratory animals gene expression Human Genetics
Content Type	Text
Resource Type	Article
Subject	Genetics Animal Science and Zoology Agronomy and Crop Science

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in