NDLI: Cerebral Aneurysms: Formation, Progression, and Developmental Chronology

Content Provider	Springer Nature Link
Author	Etminan, Nima Buchholz, Bruce A. Dreier, Rita Bruckner, Peter Torner, James C. Steiger, Hans Jakob Hänggi, Daniel Macdonald, R. Loch
Copyright Year	2013
Abstract	The prevalence of unruptured intracranial aneurysms (UIAs) in the general population is up to 3 %. Existing epidemiological data suggests that only a small fraction of UIAs progress towards rupture over the lifetime of an individual, but the surrogates for subsequent rupture and the natural history of UIAs are discussed very controversially at present. In case of rupture of an UIA, the case fatality is up to 50 %, which therefore continues to stimulate interest in the pathogenesis of cerebral aneurysm formation and progression. Actual data on the chronological development of cerebral aneurysm has been especially difficult to obtain and, until recently, the existing knowledge in this respect is mainly derived from animal or mathematical models or short-term observational studies. Here, we review the current data on cerebral aneurysm formation and progression as well as a novel approach to investigate the developmental chronology of cerebral aneurysms.
Starting Page	167
Ending Page	173
Page Count	7
File Format	PDF
ISSN	18684483
Journal	Translational Stroke Research
Volume Number	5
Issue Number	2
e-ISSN	1868601X
Language	English
Publisher	Springer US
Publisher Date	2013-10-30
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Intracranial aneurysms Aneurysm progression Aneurysm formation Developmental chronology Neurosciences Neurology Cardiology Neurosurgery Vascular Surgery
Content Type	Text
Resource Type	Article
Subject	Cardiology and Cardiovascular Medicine Neuroscience Neurology (clinical)

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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