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| Content Provider | Springer Nature Link |
|---|---|
| Author | Ekman, Rolf Persson, Rita Nilsson, Carol L. |
| Copyright Year | 2002 |
| Abstract | A number of studies have shown that early life events can affect the development of the nervous system, contributing to particular individual differences in later vulnerability to different forms of psychosocial stress related to the environment and lifestyle.Neuropeptides, chemokines (CKs), neurotrophins (NTs) belong to the chemical microenvironment of the cells of the central nervous system (CNS). This paper reviews research performed in our and other laboratories indicating that mass spectrometry should play a significant role in future studies of the structures of proteins/peptides in neuroscience. These applications include peptide metabolism associated with normal and impaired neurone/immune function. Detailed information about peptide/protein processing in the CNS may be studied by using the lymphocyte as a model reflecting different chemical modifications of peptides/proteins related to various psychosomatic disturbances reflecting disorders of environment and lifestyle. |
| Starting Page | 565 |
| Ending Page | 572 |
| Page Count | 8 |
| File Format | |
| ISSN | 10298428 |
| Journal | Neurotoxicity Research |
| Volume Number | 4 |
| Issue Number | 5-6 |
| e-ISSN | 14763524 |
| Language | English |
| Publisher | Springer-Verlag |
| Publisher Date | 2002-01-01 |
| Publisher Place | New York |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Hypothalamus-pituitary-adrenal (HPA) axis Stress Depression Schizophrenia Lymphocyte Cell nucleus Neurosciences Pharmaceutical Sciences/Technology Neurology Neurochemistry Pharmacology/Toxicology Neurobiology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neuroscience Toxicology |
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