NDLI: Some new characteristics of large genomes

Content Provider	Springer Nature Link
Author	Kozlov, N. N.
Copyright Year	2013
Abstract	This paper reports the results of calculations for some new characteristics of large genomes. Twelve genomes with a total of 203942 genes have been analyzed. The study is based on theoretical research on gene blocking published in 2010 in this journal. The calculations have shown that for all genomes the blocking is not random and not extreme. For the human genome its average value is less than a third of the maximum theoretical value and by a factor of 2.5 larger than its theoretical minimal value. It is shown that plus and minus in the DNA chain are blocked practically in the same way for all studied genomes. The participation of termination codons in blockings was found to be not equally probable. For almost all considered genomes the TGA codon was used more than 50% compared to TAA and TAG. The fact that as of September 2011 more than 1200 large genomes are being decoded in the world adds relevance to this work.
Starting Page	220
Ending Page	228
Page Count	9
File Format	PDF
ISSN	20700482
Journal	Mathematical Models and Computer Simulations
Volume Number	5
Issue Number	3
e-ISSN	20700490
Language	English
Publisher	SP MAIK Nauka/Interperiodica
Publisher Date	2013-05-23
Publisher Place	Dordrecht
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	large genomes gene blocking Mathematical Modeling and Industrial Mathematics Simulation and Modeling
Content Type	Text
Resource Type	Article
Subject	Modeling and Simulation Computational Mathematics

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