NDLI: A Randomized Pilot Study of Stochastic Vibration Therapy in Spinocerebellar Ataxia

Content Provider	Springer Nature Link
Author	Kaut, O. Jacobi, H. Coch, C. Prochnicki, A. Minnerop, M. Klockgether, T. Wüllner, U.
Copyright Year	2013
Abstract	Whole body vibration (WBV) is a biomechanical treatment used widely in professional sports and rehabilitation. We examined the effect of stochastic WBV on ataxia in spinocerebellar ataxia types 1, 2, 3, and 6 (SCA 1, 2, 3 and 6) in a single-center double-blind sham-controlled study. Stochastic WBV was applied on four sequent days, each treatment consisting of five stimulus trains of 60-s duration at a frequency of 6.5 Hz and 60-s resting time between stimuli (n = 17). Patients allocated to the sham group received the same treatment with 1 Hz (n = 15). All patients were rated at baseline and after the last treatment using clinical scores (SARA, SCAFI, and INAS). After treatment, we found significant improvements of gait, posture, and speed of speech in the verum group while limb kinetics and ataxia of speech did not respond. Stochastic WBV might act on proprioceptive mechanisms and could also stimulate non-cerebellar/compensatory mechanisms. But at present, the involved cellular mechanism and the presumed neuronal loops cannot be deciphered. Thus, future work is needed to understand the mechanisms of whole body vibration. Finally, the use of stochastic WBV could provide a supplementation to treat ataxia in SCA and can be combined with physiotherapeutical motor training.
Starting Page	237
Ending Page	242
Page Count	6
File Format	PDF
ISSN	14734222
Journal	The Cerebellum
Volume Number	13
Issue Number	2
e-ISSN	14734230
Language	English
Publisher	Springer US
Publisher Date	2013-11-07
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Spinocerebellar Ataxia Rehabilitation Functional Outcome Neurosciences Neurology Neurobiology
Content Type	Text
Resource Type	Article
Subject	Neurology Neurology (clinical)

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