NDLI: Posterior Fossa Syndrome After Cerebellar Stroke

Content Provider	Springer Nature Link
Author	Mariën, Peter Verslegers, Lieven Moens, Maarten Dua, Guido Herregods, Piet Verhoeven, Jo
Copyright Year	2013
Abstract	Posterior fossa syndrome (PFS) due to vascular etiology is rare in children and adults. To the best of our knowledge, PFS due to cerebellar stroke has only been reported in patients who also underwent surgical treatment of the underlying vascular cause. We report longitudinal clinical, neurocognitive and neuroradiological findings in a 71-year-old right-handed patient who developed PFS following a right cerebellar haemorrhage that was not surgically evacuated. During follow-up, functional neuroimaging was conducted by means of quantified Tc-99m-ECD SPECT studies. After a 10-day period of akinetic mutism, the clinical picture developed into cerebellar cognitive affective syndrome (CCAS) with reversion to a previously learnt accent, consistent with neurogenic foreign accent syndrome (FAS). No psychometric evidence for dementia was found. Quantified Tc-99m-ECD SPECT studies consistently disclosed perfusional deficits in the anatomoclinically suspected but structurally intact bilateral prefrontal brain regions. Since no surgical treatment of the cerebellar haematoma was performed, this case report is presumably the first description of pure, “non-surgical vascular PFS”. In addition, reversion to a previously learnt accent which represents a subtype of FAS has never been reported after cerebellar damage. The combination of this unique constellation of poststroke neurobehavioural changes reflected on SPECT shows that the cerebellum is crucially implicated in the modulation of neurocognitive and affective processes. A decrease of excitatory impulses from the lesioned cerebellum to the structurally intact supratentorial network subserving cognitive, behavioural and affective processes constitutes the likely pathophysiological mechanism underlying PFS and CCAS in this patient.
Starting Page	686
Ending Page	691
Page Count	6
File Format	PDF
ISSN	14734222
Journal	The Cerebellum
Volume Number	12
Issue Number	5
e-ISSN	14734230
Language	English
Publisher	Springer US
Publisher Date	2013-04-11
Publisher Place	Boston
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Posterior fossa syndrome Cerebellar cognitive affective syndrome Foreign accent syndrome Stroke SPECT Cerebellum Neurosciences Neurology Neurobiology
Content Type	Text
Resource Type	Article
Subject	Neurology Neurology (clinical)

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

The Posterior Fossa and Foreign Accent Syndrome: Report of Two New Cases and Review of the Literature

Posterior Fossa Syndrome in an Adult Patient Following Surgical Evacuation of an Intracerebellar Haematoma

Neurobehavioral alterations in an adolescent following posterior fossa tumor resection

Developmental Cerebellar Cognitive Affective Syndrome in Ex-preterm Survivors Following Cerebellar Injury

Cognitive Impairment in ARCA-1, a Newly Discovered Pure Cerebellar Ataxia Syndrome

Cerebellar Contribution to Social Cognition

Cognitive and Affective Disturbances Following Focal Brainstem Lesions: A Review and Report of Three Cases

3D Morphometric Analysis of Human Fetal Cerebellar Development

Cerebellar Cognitive Affective Syndrome in Machado Joseph Disease: Core Clinical Features

Posterior Fossa Syndrome After Cerebellar Stroke

Similar Documents

The Posterior Fossa and Foreign Accent Syndrome: Report of Two New Cases and Review of the Literature

Posterior Fossa Syndrome in an Adult Patient Following Surgical Evacuation of an Intracerebellar Haematoma

Neurobehavioral alterations in an adolescent following posterior fossa tumor resection

Developmental Cerebellar Cognitive Affective Syndrome in Ex-preterm Survivors Following Cerebellar Injury

Cognitive Impairment in ARCA-1, a Newly Discovered Pure Cerebellar Ataxia Syndrome

Cerebellar Contribution to Social Cognition

Cognitive and Affective Disturbances Following Focal Brainstem Lesions: A Review and Report of Three Cases

3D Morphometric Analysis of Human Fetal Cerebellar Development

Cerebellar Cognitive Affective Syndrome in Machado Joseph Disease: Core Clinical Features

Posterior Fossa Syndrome After Cerebellar Stroke