NDLI: Lipid abnormalities in chronic renal failure

Content Provider	Springer Nature Link
Author	Bhagwat, Rajesh Joshi, S. P. Salgia, Pradeep Sepaha, Achal
Copyright Year	1997
Abstract	Lipid abnormalities remain to be a major cause of early mortality in patients with chronic renal failure (CRF). In present study, 114 (one hundred fourteen) CRF patients without any additional cause of dyslipidemia were divided into groups on the basis of etiologies of CRF. Blood samples from each group were analyzed for total cholesterol, triglyceride and HDL cholesterol along with blood urea nitrogen and serum creatinine. 25 healthy individuals without any obvious disease were taken as control. Patients from all the groups showed a marked hypertriglyceridemia of 232 (SD±77) mg/dl (P<0.001) as compared to control. Levels of HDL cholesterol were found to be significantly low 20 (±11) mg/dl (p<0.001) in all the groups. LDL cholesterol showed an increase 104 (±30) mg/dl as compared to control group which is not statistically significant. Present study reveals that, CRF patients show an uniform dyslipidemia irrespective of etiologies leading to CRF. This dyslipidemia is also independent of serum creatinine levels. Although, these lipid abnormalities may not solely cause mortality in CRF patients, they may act as modulators in accelerating atherogenesis which in turn cause early mortality in CRF patients.
Starting Page	81
Ending Page	85
Page Count	5
File Format	PDF
ISSN	09701915
Journal	Indian Journal of Clinical Biochemistry
Volume Number	12
Issue Number	1
e-ISSN	09740422
Language	English
Publisher	Springer India
Publisher Date	1997-01-01
Publisher Place	New Delhi
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Chronic Renal Failure (CRF) High Density Lipids (HDL) Low Desity Lipids (LDL) Dyslipidemia Atherogenesis Biochemistry Microbiology Chemistry/Food Science Pathology
Content Type	Text
Resource Type	Article
Subject	Clinical Biochemistry

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