NDLI: Intravenous Leiomyomatosis of the Uterus : A Report of Three Cases

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Intravenous Leiomyomatosis of the Uterus : A Report of Three Cases

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Pathology & Oncology Research : Volume 3

Intravenous Leiomyomatosis of the Uterus : A Report of Three Cases

Content Provider	Springer Nature Link
Author	Ala Andrade, Liliana Z Torres An, Renato Fs Sales, José Vicentini, Regina A De Souza, Gustavo
Copyright Year	1998
Abstract	Three cases of intravenous leiomyomatosis (IVL) of the uterus, a rare benign smooth-muscle tumor, are described. A preoperative diagnosis of IVL was not made in any of the patients, all of which presented with a pelvic mass with the presumptive diagnosis of leiomyoma. Surgical exploration confirmed the presence of uterine mass and two of the three cases showed extra-uterine extension into the ovarian or uterine veins. Histological examination demonstrated a fascicular pattern of bland spindle-shaped smooth-muscle cells, which extended to veins inside the myometrium or to extrauterine veins. This was confirmed by immunohistochemical stain for desmin and factor VIII. Despite their histological benignity, these lesions have a tendency to metastasize and are closely related to the conditions called “benign metastasizing leiomyoma” and “intracaval mass and cardiac extension”. The primary treatment of IVL is hysterectomy and excision of any extrauterine tumor, when technically feasible. Anti-estrogenic therapy has been suggested as potentially useful in controlling of unresectable tumor. According to the literature, the follow-up must be long and periodic postoperative ultrasonic or magnetic nuclear resonance imaging studies may be useful in detecting growth of residual intravascular tumor.
Starting Page	44
Ending Page	47
Page Count	4
File Format	PDF
ISSN	12194956
Journal	Pathology & Oncology Research
Volume Number	4
Issue Number	1
e-ISSN	15322807
Language	English
Publisher	Springer Netherlands
Publisher Date	1998-01-01
Publisher Place	Dordrecht
Access Restriction	Subscribed
Subject Keyword	uterine tumor intravenous leiomyomatosis Cancer Research Oncology Pathology Immunology Biomedicine general
Content Type	Text
Resource Type	Report
Subject	Cancer Research Pathology and Forensic Medicine Oncology

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