NDLI: Molecular epidemiology and sequencing of the G-L intergenic region of rabies viruses isolated in China

Content Provider	Springer Nature Link
Author	Meng, Sheng Li Xu, Ge Lin Yan, Jia Xin Ming, Ping Gang Wu, Jie Yang, Xiao Ming Ming, He Tian Zhu, Feng Cai Zhou, Dun Jin Xiao, Qi You Dong, Guan Mu
Copyright Year	2007
Abstract	A group of 25 rabies viruses (RABVs), recovered from 24 dogs and one human case, were collected from various areas in China between 2004 and 2006. Genetic and phylogenetic analyses of the G-L intergenic region were carried out in 25 street RABV isolates and CTN vaccine strains of 7 generations. The study was based on the comparison of a 519 bp nucleotide sequence, encompassing the G-L intergenic region. The nucleotide sequence homologies of Chinese street strains were from 95.5% to 100%. The phylogenetic analysis showed that all Chinese isolates clearly supported the placement of all Chinese viruses in Lyssavirus genotype 1 and they were distributed according to their geographical origins. All of the Chinese strains were closely related but they could still be divided into two groups: group of street strains and group of CTN strains. This study presents details about the molecular epidemiology of rabies viruses based on the sequences of the G-L Intergenic region.
Starting Page	26
Ending Page	33
Page Count	8
File Format	PDF
ISSN	16740769
Journal	Virologica Sinica
Volume Number	22
Issue Number	1
e-ISSN	1995820X
Language	English
Publisher	SP Wuhan Institute of Virology, CAS
Publisher Date	2009-09-16
Publisher Place	Heidelberg
Access Restriction	Subscribed
Subject Keyword	Rabies virus Molecular Epidemiology G-L intergenic region China Microbial Genetics and Genomics Microbiology Biochemistry Oncology Medical Microbiology Virology
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Virology Immunology Molecular Medicine

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